The combination of a new genetically encoded voltage indicator and fast two-photon imaging methods enables detection of rapid neural electrical activity in organotypic slice cultures and in living flies.

ArcLight, a popular optogenetic reporter of voltage, is studied at both single-molecule and macroscopic levels, which leads to new mechanistic understanding and to the rational design of a faster reporter.

The link between the activity of large populations of cortical neurons and single neuron responses is examined in primates using a new optical-genetic method.

Fluorescence lifetime imaging microscopy, paired with fluorescent, voltage-sensitive dyes, provides a method for measuring and quantifying membrane potentials of living cells.

Common adeno-associated viral transduction procedures induce artefactual spatially confined Ca²⁺ waves in the hippocampus.

Transmembrane protein 266 contains a functional S1-S4 voltage-sensing domain that is regulated by extracellular Zn²⁺ ions.

A near-infrared light-stimulable optogenetic platform enables remote and wireless manipulation of calcium signaling and immune responses both in vitro and in vivo to achieve tailored function.

Genetic, behavioral, and biochemical evidence reveals that the Drosophila TRPγ channel is required in neuroendocrine cells for the starvation-induced switch in preference to less palatable but more nutritive food.

Experience alters neurotransmitter release from different axonal compartments in different ways, allowing a set of neurons to coherently modulate behavior through diverse actions on multiple downstream circuits.

Curves and corners are separately encoded by neurons clustered into functional domains in macaque V4.