1,483 results found
    1. Microbiology and Infectious Disease

    Comprehensive annotations of human herpesvirus 6A and 6B genomes reveal novel and conserved genomic features

    Yaara Finkel et al.
    Unbiased mapping of viral open reading frames (ORFs) and transcripts in HHV-6 genomes uncovers novel ORFs and lncRNAs that are conserved across betaherpesviruses.
    1. Microbiology and Infectious Disease

    Transcriptomics: Revisiting the genomes of herpesviruses

    Bhupesh K Prusty, Adam W Whisnant
    Combining integrative genomics and systems biology approaches has revealed new and conserved features in the genome of human herpesvirus 6.
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    1. Computational and Systems Biology

    Systematic morphological profiling of human gene and allele function via Cell Painting

    Mohammad Hossein Rohban et al.
    Gene function can be revealed based on characteristic phenotypes using a Cell Painting microscopy assay.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2 pandemic

    Chase W Nelson et al.
    A novel, overlapping, putatively functional gene in SARS-CoV-2, ORF3d, is absent from close relatives of SARS-CoV-2 and may have contributed to the biology, emergence, or spread of the virus.
    1. Developmental Biology

    Building the vertebrate codex using the gene breaking protein trap library

    Noriko Ichino et al.
    The analysis of the first 1000 revertible protein trap alleles in zebrafish resulted in new functional genomic annotations and produced a panel of potential new models of human disease.
    1. Developmental Biology

    An improved zebrafish transcriptome annotation for sensitive and comprehensive detection of cell type-specific genes

    Nathan D Lawson et al.
    Computational efforts yield a zebrafish transcriptome annotation that provides more sensitive and comprehensive gene detection over existing annotations when used for bulk or single-cell RNA-seq.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Dynamics of genomic innovation in the unicellular ancestry of animals

    Xavier Grau-Bové et al.
    The foundations of genomic complexity in multicellular animals have deep roots in their unicellular prehistory, both in terms of innovations in gene content, as well as the evolutionary dynamics of genome architecture.
    1. Computational and Systems Biology

    Science Forum: Wikidata as a knowledge graph for the life sciences

    Andra Waagmeester et al.
    Wikidata is continuously-updated resource that could improve the efficiency and accuracy of research in many areas of the life and biomedical sciences.

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