Absolute quantification of CTCF and cohesin reveals quantitative constraints on 3D genome organization and illuminates the molecular architecture of the cohesin complex.

Yeast homologous chromosomes exhibit condition-specific mitotic pairing at both global and local scales.

A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.

Hey together with LaminC continuously supervise nuclear organisation and differentiated enterocyte identity, a regulation that is lost upon ageing, resulting in loss of gut homeostasis.

Absolute quantification of cohesin, CTCF, NIPBL, WAPL and sororin in HeLa cells implies that some genomic cohesin and CTCF enrichment sites are unoccupied at any one time.

Single-molecule imaging of CTCF and cohesin in live cells suggests that chromatin loops are dynamic structures that frequently form and fall apart.

Metabolic gradients underlie gene expression patterns within spatially controlled expanding 2D microbial colonies.

Replication origins are fundamental organizers and regulators of gene activity through embryonic development.

A new method that measures multiple aspects of chromatin organization in single cells has a possible application to study regulatory processes in heterogeneous samples.

Identification of novel components and regulators of heterochromatin reveals a spatially complex and dynamic organization.