Genetic incompatibilities are common and widely distributed throughout the genomes of swordtail fish, and prevent the regions of the genome around them from being exchanged between different species.
Genome sequencing reveals the evolution and epidemiology of Leishmania donovani in the Indian subcontinent, where epidemics have caused up to 30,000 deaths per year.
Markus Pfenninger, Friederike Reuss ... Barbara Feldmeyer
European beech harbours substantial genetic variation at genomic loci associated with drought resistance and newly identified loci can help to accelerate and monitor adaptation to climate change.
Copy number alteration heterogeneity exists in many shapes and forms in breast cancer genomes and single-cell genomics is a powerful tool to further our understanding of its nature and significance.
Gillian Morven Belbin, Jacqueline Odgis ... Eimear E Kenny
A health-system embedding method for genomic discovery and clinical characterization of disease highlights the importance of documenting a wider spectrum of genetic disorders in diverse populations.
Mark McMullan, Anastasia Gardiner ... Jonathan DG Jones
Hybridization and introgression blur species boundaries and broaden genetic diversity available for adaptation; and widespread introgression underpins the evolution of races of the generalist pathogen Albugo candida that specialise on different host plant species.
Xavier Grau-Bové, Guifré Torruella ... Iñaki Ruiz-Trillo
The foundations of genomic complexity in multicellular animals have deep roots in their unicellular prehistory, both in terms of innovations in gene content, as well as the evolutionary dynamics of genome architecture.
