3,670 results found
    1. Genetics and Genomics
    2. Evolutionary Biology

    Hybridization breaks species barriers in long-term coevolution of a cyanobacterial population

    Gabriel Birzu, Harihara Subrahmaniam Muralidharan ... Devaki Bhaya
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Neuroscience

    A stochastic neuronal model predicts random search behaviors at multiple spatial scales in C. elegans

    William M Roberts, Steven B Augustine ... Shawn R Lockery
    A stochastic model of locomotory control in C. elegans based on an extensive new set of tracking data can explain and predict effects of ablations and mutations on behavior.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator

    Adrian L Sanborn, Benjamin T Yeh ... Roger D Kornberg
    Transcriptional activation domains achieve rapid, dynamic, specific interaction with Mediator through binding of an unstructured peptide to multiple hydrophobic surfaces without particular amino acid side chain interactions.
    1. Neuroscience

    The unique synaptic circuitry of specialized olfactory glomeruli in Drosophila melanogaster

    Lydia Gruber, Rafael Cantera ... Jürgen Rybak
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    A neural correlate of individual odor preference in Drosophila

    Matthew A Churgin, Danylo O Lavrentovich ... Benjamin de Bivort
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    Dynamical feature extraction at the sensory periphery guides chemotaxis

    Aljoscha Schulze, Alex Gomez-Marin ... Matthieu Louis
    A computational model for the control of chemotaxis in the Drosophila larva clarifies the link between the peripheral encoding of naturalistic olfactory stimuli and action selection.
    1. Neuroscience

    Normative evidence accumulation in unpredictable environments

    Christopher M Glaze, Joseph W Kable, Joshua I Gold
    Theoretically optimal dynamics for making decisions in unpredictable environments provide a broadly applicable framework for understanding choice behavior and underlying neural signals.
    1. Neuroscience

    Suggestion of creatine as a new neurotransmitter by approaches ranging from chemical analysis and biochemistry to electrophysiology

    Xiling Bian, Jiemin Zhu ... Yi Rao
    While neurotransmitters were discovered decades ago, evidence suggests that more transmitters are to be discovered using the presented approaches.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Genome-wide Functional Characterization of Escherichia coli Promoters and Sequence Elements Encoding Their Regulation

    Guillaume Urtecho, Kimberly D. Insigne ... Sriram Kosuri
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Functional and anatomical specificity in a higher olfactory centre

    Shahar Frechter, Alexander Shakeel Bates ... Gregory Jefferis
    The Drosophila lateral horn, a higher olfactory brain area, contains >165 genetically defined cell types with stereotyped odour responses across animals and improved odor categorisation compared with their inputs.

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