PCGF6 links sequence specific target recognition by the MAX/MGA transcription factor complex to PRC1 (polycomb repressive complex 1) -dependent transcriptional silencing of germ cell-specific genes in mouse pluripotent stem cells.

Wnt signaling regulates cellular redox in the germline stem cell differentiation niche via a novel regulatory mechanism, thereby controlling germ line stem cell progeny differentiation.

The Mtgr1 protein promotes the maintenance of pluripotency and germ cell formation via its interaction with the stem cell regulator Prdm14.

Genetic and cell biological study indicates that germ cells' connectivity serves as a mechanism to increase the sensitivity of germline to DNA damage, protecting the genome of gametes, in the Drosophila testis.

The scaffolding protein Oskar organizes two types of germ granules by phase transition within the same cell but with distinct morphologies, composition and biological functions.

Increased Notch signaling enhances germ cell reprograming in C. elegans by antagonizing PRC2-mediated repression, which results in the activation of UTX-1 and other reprograming-promoting genes.

A novel mechanism of local plasticity in the distal dendrites of hippocampal granule cells.

Long-term hair follicle stem cells arise by embryonic progenitor cells occupying a niche location that is defined by attenuated Wnt/β-catenin signal.

Long-term exposure to recipient's alloantigens promotes major metabolic defects in T cells that are independent of PD-1-mediated regulation.

Germ cell ablation delays C. elegans aging, in part, because unconsumed fat triggers activation of the detoxification factor SKN-1/Nrf, which is regulated by lipid signals and maintains lipid homeostasis.