Chromatin changes downstream from Drosophila germline stem cells and fertilized zygotes alter how transposable element activity and gene expression are controlled to facilitate differentiation.

Two SET-domain containing proteins regulate H3K4me3 by their binding to H3K4me3 through their PHD domain and directly regulate expression of a subset of genes.

Early oocyte development takes place in germline cysts and is strikingly conserved from Drosophila to mouse, reflecting common mechanisms that may help reverse aging and specify oocyte and early embryo polarity.

Selective transfer of mitochondria in the Balbiani body ensures high-quality oocyte mitochondria at extreme ploidy, explaining many enigmatic features of female germline architecture including germ cell loss.

The H3K36 and H3K27 histone methyltransferases MES-4 and PRC2 protect survival of the nascent germline in Caenorhabditis elegans by repressing expression of X-linked genes, including the key transcription factor LIN-15B.

Many well-studied maternal developmental pathways that are required for embryonic development in Drosophila are regulated by the transcription factor OVO in the Drosophila female germline.

Distinct stem cell populations drive larval, somatic, and germline development of the human parasitic flatworm, Schistosoma mansoni.

RNP granules confer temporal and spatial regulation of oskar mRNA degradation to minimize inheritance of oskar mRNAby germ cells and thereby protect germline development.

Non-canonical ‘testis-specific’ actin-related protein (Arp), Arp53D, is critical for early embryonic development in Drosophila, revealing important roles for lineage-specific, divergent, testis-expressed non-canonical Arps outside the male germline in animals.

snpc-1.3 specifies male piRNA transcription and is regulated by the sex determination pathway.