Morphological and functional rejuvenation upon exit from adult reproductive diapause in C. elegans is independent of germline signaling, but instead involves somatic nucleolar activation and expansion of the RNA pool.
De novo transcriptome assembly and comprehensive characterization of gene expression in proliferating cells of regeneration-capable flatworm Macrostomum lignano advance this organism as a powerful model for stem cell research.
A Drosophila fertility gene is identified that acts as a linker between HP1a and local H3K4 demethylation during HP1a-mediated gene silencing that is required for ovary development and transposon silencing..
GCNA proteins comprise a previously unnoticed family of proteins that has been enriched in cells carrying a heritable genome since the invention of sexual reproduction in eukaryotes, and has had reproductive function for at least 600 million years.
Characterization of Drosophila female germ cell differentiation shows that nurse cells initiate Polycomb silencing by regulating Pcl and Scm levels to alter the biochemical properties of the PRC2 H3K27 methylase.