Fluctuations of a transcription factor that coincide with the G2 phase of the cell cycle pattern two interspersed cell fates in a multicellular system.

Functional reconstitution of a mammalian P2X7 receptor uncovers an intrinsic and lipid-dependent dye-permeable membrane pore.

Noise in a signaling network comprising thousands of molecules shapes diversity across cell populations and generates giant temporal fluctuations at the single-cell level.

Journals can benefit from listening to graduate students, postdocs and newly-independent group leaders.

The views of peers are important when applying for a faculty position, but so are research plans and being a good 'fit'.

Staff from the Mayo Clinic in the US and the Karolinska Institute in Sweden describe a joint transatlantic course intended to broaden the horizons of the next generation of researchers in the field of regenerative medicine.

There are many reasons for submitting your best work to eLife, especially if you are an early career researcher.

When making decisions about funding and jobs the scientific community should recognise that most of the tools used to evaluate scientific excellence are biased in favour of established disciplines and against interdisciplinary research.

The Janelia Research Campus opened its doors 12 years ago: we describe the philosophy underpinning Janelia, the lessons learned, and plans for the future.