1,134 results found
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish

    Shuguang Yu, Jie He
    The analysis of injury-reactivated tectal radial glia in zebrafish reveals a stochastic cell-cycle entry and cell-state-dependent regulation of the balance between neurogenesis and gliogenesis.
    1. Developmental Biology
    2. Neuroscience

    Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia

    Xin Heng et al.
    Genome-wide transcriptional profiling and genetic analyses reveal conserved mechanisms underlying the generation of neocortical basal radial glia and cerebellar Bergmann glia.
    1. Cell Biology
    2. Neuroscience

    Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior

    Stephan Raiders et al.
    A peripheral sense-organ glia actively engulfs fragments of a sensory neuron ending to modify neuron shape and associated animal sensory behavior in Caenorhabditis elegans..
    1. Cell Biology
    2. Neuroscience

    Local and global influences on protein turnover in neurons and glia

    Aline R Dörrbaum et al.
    A dynamic SILAC analysis reveals that neuronal proteome turnover is influenced by the cell type as well as the extracellular environment.
    1. Developmental Biology
    2. Neuroscience

    Spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia

    Laura Fontenas, Sarah Kucenas
    Motor exit point (MEP) glia utilize mechanisms most commonly attributed to neural crest cells for their development from spinal cord precursors.
    1. Neuroscience

    A muscle-epidermis-glia signaling axis sustains synaptic specificity during allometric growth in Caenorhabditis elegans

    Jiale Fan et al.
    The work uncovers a muscle-epidermis-glia signaling axis, modulated by protease mig-17 and the basement membrane, that regulates synaptic allometry during growth in Caenorhabditis elegans.
    1. Developmental Biology

    Hedgehog signaling regulates gene expression in planarian glia

    Irving E Wang et al.
    Hedgehog signaling plays a role in regulating glia gene expression in planarians, pointing to a candidate ancestral and broadly used role for the Hedgehog pathway.
    1. Neuroscience

    NG2 glia are required for vessel network formation during embryonic development

    Shilpi Minocha et al.
    The appearance of NG2+ glial cells in the dorsal telencephalon of the embryo coincides with the establishment of the brain blood vessel network in mice.
    1. Cell Biology
    2. Neuroscience

    Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses

    Kirby M Donnelly et al.
    Prion-like transfer of mutant huntingtin aggregates from presynaptic to postsynaptic neurons is enhanced by neuronal silencing and requires passage through the cytoplasm of Draper-expressing phagocytic glia in adult Drosophila brains.
    1. Stem Cells and Regenerative Medicine

    Activating the regenerative potential of Müller glia cells in a regeneration-deficient retina

    Katharina Lust, Joachim Wittbrodt
    Müller glia cells in the medaka (Oryzias latipes) retina act as lineage restricted progenitors which only regenerate photoreceptors but can be activated to perform as potent stem cells using Sox2.

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