192 results found
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila

    Zaijun Ma et al.
    Epigenetic drift of H3K27me3 is one of the molecular mechanisms that contribute to aging, and stimulation of glycolysis promotes metabolic health and longevity.
    1. Chromosomes and Gene Expression

    Msn2/4 regulate expression of glycolytic enzymes and control transition from quiescence to growth

    Zheng Kuang et al.
    General stress response factors Msn2 and Msn4 activate glycolytic genes and promote acetyl-CoA accumulation to stimulate growth and proliferation of yeast cells under a nutrient-limiting condition, suggesting the unexpected interrelationship between carbohydrate metabolism and stress response.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

    Yin P Hung et al.
    Individual cells display heterogeneous fluctuations in metabolic activity, with amplitude and kinetics controlled by interlocking feedbacks between glycolysis and the Insulin/PI3K/Akt signaling pathway.
    1. Developmental Biology

    Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

    Xinde Zheng et al.
    The shutoff of aerobic glycolysis in neuronal differentiation is essential for neuronal survival.
    1. Biochemistry and Chemical Biology
    2. Human Biology and Medicine

    Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step

    Alexander A Shestov et al.
    A new computational model of the Warburg Effect reveals that the rate-limiting step of glycolysis is variable, identifies new control mechanisms, and could help to predict the responses to targeting glycolysis to treat cancer.
    1. Computational and Systems Biology

    Estimating the protein burden limit of yeast cells by measuring the expression limits of glycolytic proteins

    Yuichi Eguchi et al.
    Measurement of expression limits of yeast glycolytic proteins reveal the protein burden limit, which is the expression limit of any protein in the cell.
    1. Cell Biology
    2. Immunology and Inflammation

    Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation

    Lindsey Araujo et al.
    Metabolic switches between oxidative phosphorylation and aerobic glycolysis plus glutaminolysis direct T cell function by altering the flux of glucose and glutamine to N-glycosylation.
    1. Cell Biology
    2. Neuroscience

    Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing

    Piergiorgio La Rosa et al.
    The RNA binding protein Sam68 links a key metabolic route to the neural stem cell fate in the developing mouse brain.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death

    Laura E Sanman et al.
    A signal for inflammatory cell death is induced by the disruption of cellular metabolism.
    1. Cell Biology
    2. Neuroscience

    Glycolytic reliance promotes anabolism in photoreceptors

    Yashodhan Chinchore et al.
    Aerobic glycolysis in rod photoreceptors of adult mice is regulated by allostery and FGF signaling and is required for maintaining outer segments.

Refine your results by:

Type
Research categories