59 results found
    1. Microbiology and Infectious Disease

    ATP burst is the dominant driver of antibiotic lethality in Mycobacterium smegmatis

    Tejan Lodhiya, Aseem Palande ... Raju Mukherjee
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

    Vivian Salgueiro, Jorge Bertol ... Rafael Prados-Rosales
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis

    Nelson V Simwela, Eleni Jaecklein ... David G Russell
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways

    Rakesh Kumar, Fan Zhang ... Alan G Hinnebusch
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Stem Cells and Regenerative Medicine

    Switching of RNA splicing regulators in immature neuroblasts during adult neurogenesis

    Corentin Bernou, Marc-André Mouthon ... François Dominique Boussin
    Characterization of an abundant clonogenic and multipotent population of immature neuroblasts, at the transition between transient-amplifying progenitor (TAP) neuroblasts and migratory neuroblasts, reversibly engaged in neuronal differentiation.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Temporal transcriptional response of Candida glabrata during macrophage infection reveals a multifaceted transcriptional regulator CgXbp1 important for macrophage response and fluconazole resistance

    Maruti Nandan Rai, Qing Lan ... Koon Ho Wong
    The dynamic transcription responses of the human fungal pathogen Candida glabrata during macrophage infection is revealed and a novel transcription factor important for the responses to macrophage, proliferation within macrophage, as well as anti-fungal drug resistance has been discovered.
    1. Cell Biology

    SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus

    Dandan Wu, Chi Yang ... Zhenhong Zhuang
    Chromatin immunoprecipitation sequencing and RNA sequencing have elucidated the complex transcript regulation pathways orchestrated by SntB, pivotal for Aspergillus flavus's development, mycotoxin production, and virulence.
    1. Microbiology and Infectious Disease

    Functional genomics reveals the mechanism of hypoxic adaptation in nontuberculous mycobacteria

    Yoshitaka Tateishi, Yuriko Ozeki ... Sohkichi Matsumoto
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    A translation proofreader of archaeal origin imparts multi-aldehyde stress tolerance to land plants

    Pradeep Kumar, Ankit Roy ... Rajan Sankaranarayanan
    Genetic, biochemical, and bioinformatic analyses reveal how expanding metabolic repertoire interferes with fundamental processes like protein synthesis inside cells and the role of D-aminoacyl-tRNA deacylase2 in protecting these processes during terrestrialisation.

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