999 results found
    1. Neuroscience

    The role of higher-order thalamus during learning and correct performance in goal-directed behavior

    Danilo La Terra, Ann-Sofie Bjerre ... Lucy M Palmer
    The higher order thalamus encodes and influences correct action during learning and performance in a sensory-based goal-directed behavior.
    1. Neuroscience

    Stress diminishes outcome but enhances response representations during instrumental learning

    Jacqueline Katharina Meier, Bernhard P Staresina, Lars Schwabe
    Decoding of neural outcome and response representations allows dissecting goal-directed and habitual contributions to behaviour and reveals how acute stress biases the instrumental control of behaviour.
    1. Neuroscience

    Modular organization of cerebellar climbing fiber inputs during goal-directed behavior

    Shinichiro Tsutsumi, Naoki Hidaka ... Kazuo Kitamura
    Motor and non-motor functions are represented in spatially segregated and temporally organized climbing fiber signals to distinct cerebellar zones during goal-directed behavior.
    1. Neuroscience

    Thalamocortical and corticothalamic pathways differentially contribute to goal-directed behaviors in the rat

    Fabien Alcaraz, Virginie Fresno ... Mathieu Wolff
    Adaptive decision-making critically depends on antiparallel flows conveying distinct information within thalamocortical circuits, highlighting directionality of functional exchanges as a neural principle potentially at play in virtually any brain circuit with reciprocal projections.
    1. Neuroscience

    Characterizing a psychiatric symptom dimension related to deficits in goal-directed control

    Claire M Gillan, Michal Kosinski ... Nathaniel D Daw
    A dimensional approach to psychiatry demonstrates the specificity and generalizability of a neurocognitive marker of compulsive behavior and intrusive thought via large-scale online testing.
    1. Neuroscience

    Tuning of olfactory cortex ventral tenia tecta neurons to distinct task elements of goal-directed behavior

    Kazuki Shiotani, Yuta Tanisumi ... Hiroyuki Manabe
    Individual neurons of ventral tenia tecta which is a part of olfactory cortex tune to specific time windows in the behavioral context during odor-guided goal-directed behaviors.
    1. Neuroscience

    Target-specific membrane potential dynamics of neocortical projection neurons during goal-directed behavior

    Takayuki Yamashita, Carl CH Petersen
    A learning-induced, motor-related, projection-specific signal from S1 to S2 accompanies reward-based-learning of a goal-directed sensorimotor transformation of whisker sensation into licking motor output.
    1. Neuroscience

    Mediodorsal thalamus is required for discrete phases of goal-directed behavior in macaques

    Evan Wicker, Janita Turchi ... Patrick A Forcelli
    Transient suppression of activity in the macaque mediodorsal thalamus impairs adjustment of secondary reinforcer values and disrupts appropriate action selection in a reinforcer devaluation task; this profile is distinct from that of amygdala or subregions of orbitofrontal cortex.
    1. Neuroscience

    Computational mechanisms of curiosity and goal-directed exploration

    Philipp Schwartenbeck, Johannes Passecker ... Karl J Friston
    Distinct computational levels of uncertainty compel agents to gain information about hidden states in the world (‘active inference’) or optimise their ‘world model’ as such (‘active learning’).
    1. Neuroscience

    Striatal direct and indirect pathway neurons differentially control the encoding and updating of goal-directed learning

    James Peak, Billy Chieng ... Bernard W Balleine
    Direct and indirect pathway neurons in posterior dorsomedial striatum were found to play distinct roles, with the former necessary for encoding and the latter for updating goal-directed learning.

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