Jacqueline Katharina Meier, Bernhard P Staresina, Lars Schwabe
Decoding of neural outcome and response representations allows dissecting goal-directed and habitual contributions to behaviour and reveals how acute stress biases the instrumental control of behaviour.
Charlotte Arlt, Roberto Barroso-Luque ... Christopher D Harvey
The areas of the cerebral cortex that are necessary for mice to perform goal-directed navigation differ depending on previous experience in cognitively challenging tasks.
Claire M Gillan, Michal Kosinski ... Nathaniel D Daw
A dimensional approach to psychiatry demonstrates the specificity and generalizability of a neurocognitive marker of compulsive behavior and intrusive thought via large-scale online testing.
Corey Fernandez, Jiefeng Jiang ... Anthony D Wagner
Mnemonic mechanisms of differentiation and integration within the medial temporal lobe occur concurrently during the learning of local and global environmental knowledge.
Opeyemi O Alabi, M Felicia Davatolhagh ... Marc Vincent Fuccillo
Disruption of the disease-associated synaptic adhesion molecule Neurexin1a in cortical excitatory neurons perturbs decision making and disrupts value-associated neural activity in downstream striatal circuits.
Philipp Schwartenbeck, Johannes Passecker ... Karl J Friston
Distinct computational levels of uncertainty compel agents to gain information about hidden states in the world (‘active inference’) or optimise their ‘world model’ as such (‘active learning’).
In a drug choice setting, rats’ preference is initially driven by deliberative processes but shifts to more automatic selection processes after extended training, in accordance with the sequential choice model.
Direct and indirect pathway neurons in posterior dorsomedial striatum were found to play distinct roles, with the former necessary for encoding and the latter for updating goal-directed learning.