996 results found
    1. Neuroscience

    Stress diminishes outcome but enhances response representations during instrumental learning

    Jacqueline Katharina Meier, Bernhard P Staresina, Lars Schwabe
    Decoding of neural outcome and response representations allows dissecting goal-directed and habitual contributions to behaviour and reveals how acute stress biases the instrumental control of behaviour.
    1. Neuroscience

    Visual attention modulates the integration of goal-relevant evidence and not value

    Pradyumna Sepulveda, Marius Usher ... Benedetto De Martino
    Visual attention modulates the integration of the evidence that is most useful for achieving a goal in both perceptual and value-based decisions.
    1. Neuroscience

    Cognitive experience alters cortical involvement in goal-directed navigation

    Charlotte Arlt, Roberto Barroso-Luque ... Christopher D Harvey
    The areas of the cerebral cortex that are necessary for mice to perform goal-directed navigation differ depending on previous experience in cognitively challenging tasks.
    1. Neuroscience

    Characterizing a psychiatric symptom dimension related to deficits in goal-directed control

    Claire M Gillan, Michal Kosinski ... Nathaniel D Daw
    A dimensional approach to psychiatry demonstrates the specificity and generalizability of a neurocognitive marker of compulsive behavior and intrusive thought via large-scale online testing.
    1. Neuroscience

    Representational integration and differentiation in the human hippocampus following goal-directed navigation

    Corey Fernandez, Jiefeng Jiang ... Anthony D Wagner
    Mnemonic mechanisms of differentiation and integration within the medial temporal lobe occur concurrently during the learning of local and global environmental knowledge.
    1. Neuroscience

    Disruption of Nrxn1α within excitatory forebrain circuits drives value-based dysfunction

    Opeyemi O Alabi, M Felicia Davatolhagh ... Marc Vincent Fuccillo
    Disruption of the disease-associated synaptic adhesion molecule Neurexin1a in cortical excitatory neurons perturbs decision making and disrupts value-associated neural activity in downstream striatal circuits.
    1. Neuroscience

    The role of higher-order thalamus during learning and correct performance in goal-directed behavior

    Danilo La Terra, Ann-Sofie Bjerre ... Lucy M Palmer
    The higher order thalamus encodes and influences correct action during learning and performance in a sensory-based goal-directed behavior.
    1. Neuroscience

    Computational mechanisms of curiosity and goal-directed exploration

    Philipp Schwartenbeck, Johannes Passecker ... Karl J Friston
    Distinct computational levels of uncertainty compel agents to gain information about hidden states in the world (‘active inference’) or optimise their ‘world model’ as such (‘active learning’).
    1. Ecology
    2. Neuroscience

    Probing the decision-making mechanisms underlying choice between drug and nondrug rewards in rats

    Youna Vandaele, Magalie Lenoir ... Serge H Ahmed
    In a drug choice setting, rats’ preference is initially driven by deliberative processes but shifts to more automatic selection processes after extended training, in accordance with the sequential choice model.
    1. Neuroscience

    Striatal direct and indirect pathway neurons differentially control the encoding and updating of goal-directed learning

    James Peak, Billy Chieng ... Bernard W Balleine
    Direct and indirect pathway neurons in posterior dorsomedial striatum were found to play distinct roles, with the former necessary for encoding and the latter for updating goal-directed learning.

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