Gamete release in the jellyfish Clytia is mediated by an opsin photopigment expressed in neurosecretory cells of the gonad ectoderm, which release an oocyte maturation hormone in response to light.
An algorithm for analysing brain connectivity data identifies cell types and connections in simple (C. elegans) and complex (mouse) nervous systems, and can even resolve structure and connectivity in a man-made microprocessor.
Single-cell sequencing and functional analysis identify T cells that can be useful for marker selection and cell therapy in uveal melanoma, a disease largely unresponsive to conventional immune checkpoint therapies.
The fate of duplicated transcription factors within budding yeast is described, providing insights into the mechanisms that shape transcriptional networks during evolution.
As Caenorhabditis elegans adult hermaphrodite germ cells leave the stem cell niche, they associate with a pair of somatic gonad cells that were thought to be symmetrical, but that actually take on dramatically different positions in the organ.
Siti N Othman, Spartak N Litvinchuk ... Amael Borzee
A robust framework of integrative phylogeography and advanced taxonomy to resolve the historical biogeography and species boundaries of true toads across the Eastern Palearctic.
Ca2+ channels and release sensors at a fast central synapse are tightly coupled, which minimizes the effect of extracellular Ca2+ concentration on the timing of transmitter release.
A computational strategy for extracting representative numerical features from 3D microscopy data enables in-depth quantitative analysis of cell and tissue organization through machine learning-driven data integration and context-guided visualization.
The mirror-symmetric structure of the Caenorhabditis elegans gonad is established through the Wnt-independent function of a Frizzled protein and three Wnt proteins with distinct roles.