727 results found
    1. Microbiology and Infectious Disease

    Strong inter-population cooperation leads to partner intermixing in microbial communities

    Babak Momeni, Kristen A Brileya ... Wenying Shou
    Simulations and experiments on systems containing two different populations of microorganisms show that interactions that benefit at least one of the populations can lead to communities with stable compositions, and that strong cooperation between two populations can lead to communities in which both populations are mixed together.
    1. Cell Biology
    2. Developmental Biology

    Ovulation in Drosophila is controlled by secretory cells of the female reproductive tract

    Jianjun Sun, Allan C Spradling
    Secretory cells in the fruit fly reproductive tract produce secretions that control ovulation through a conserved mechanism that could provide insights into ovarian cancer.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage

    Ashley L St John, Abhay PS Rathore ... Soman N Abraham
    Proteins produced by mast cells modulate the permeability of blood vessels, and may determine whether patients infected with dengue virus develop life-threatening complications.
    1. Cell Biology

    TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells

    Sandra Mitrovic, Cristina Nogueira ... Vivek Malhotra
    Goblet cells secrete mucins—which are key components of mucus—in a process that is regulated by calcium ions, which enter the goblet cells via a mechanism involving a channel protein called TRPM5.
    1. Plant Biology

    Arabidopsis plants perform arithmetic division to prevent starvation at night

    Antonio Scialdone, Sam T Mugford ... Martin Howard
    Plants implement arithmetic division to optimize use of carbohydrate reserves and thus maintain metabolism and growth at night.
    1. Neuroscience

    Dismantling the Papez circuit for memory in rats

    Seralynne D Vann
    In contrast to current models, inputs from midbrain limbic structures, but not from the hippocampus, are necessary for mammillary body contributions to memory.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa

    Budd A Tucker, Robert F Mullins ... Edwin M Stone
    Skin cells from a patient with retinitis pigmentosa have been used to generate induced pluripotent stem cells, which could potentially form the basis of new treatments for this disease.
    1. Developmental Biology

    Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells

    Jonghyeob Lee, Takuya Sugiyama ... Seung K Kim
    Cells from the human pancreatic duct can be grown in culture and triggered to become insulin-producing cells, which could potentially be transplanted into patients with diabetes.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

    Safia Deddouche, Delphine Goubau ... Caetano Reis e Sousa
    A viral RNA has been identified as a specific MDA5 agonist in cells infected with encephalomyocarditis virus.

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