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    1. Neuroscience

    Ionotropic Receptor-dependent moist and dry cells control hygrosensation in Drosophila

    Zachary A Knecht, Ana F Silbering ... Paul A Garrity
    The neurons and receptors mediating moist air detection in Drosophila are identified, revealing that moist and dry air detection depend on overlapping Ionotropic Receptors and that these pathways are both critical for hygrosensation.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications

    Kaori Noridomi, Go Watanabe ... Lin Chen
    Autoantibodies from myasthenia gravis patients bind a common core region on the nicotinic acetylcholine receptor through a largely conserved mechanism.
    1. Microbiology and Infectious Disease

    Prion propagation can occur in a prokaryote and requires the ClpB chaperone

    Andy H Yuan, Sean J Garrity ... Ann Hochschild
    The bacterium Escherichia coli possesses a permissive cytoplasmic environment and the requisite molecular machinery to support the propagation of prions.
    1. Neuroscience

    Thermotaxis: Some like it hot, but not too hot

    Chloe Greppi, Gonzalo Budelli, Paul A Garrity
    Version of Record
    Insight
    1. Neuroscience

    Cerebellar re-encoding of self-generated head movements

    Guillaume P Dugué, Matthieu Tihy ... Clément Léna
    The cerebellum encodes self-generated head rotations in a head posture-dependent manner, providing in particular a representation of how the head rotates about axes referenced relative to gravity.
    1. Neuroscience

    Memory: A divalent boost from magnesium

    Willem J Laursen, Paul A Garrity
    Enhanced levels of dietary magnesium improve long-term memory in fruit flies.
    Version of Record
    Insight
    1. Neuroscience

    Object representation in a gravitational reference frame

    Alexandriya MX Emonds, Ramanujan Srinath ... Charles E Connor
    Neural recordings in monkey IT show that the primate visual system transforms object representations into a reference frame aligned with gravity and independent of how the head and eyes are tilted.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Characterizing human mobility patterns in rural settings of sub-Saharan Africa

    Hannah R Meredith, John R Giles ... Amy Wesolowski
    Mobile phone data reveal aspects of human mobility patterns in Sub-Saharan Africa missed by standard spatial models however, model estimates can be improved by accounting for trip urbanicity and region.
    1. Plant Biology

    Rapid translocation of NGR proteins driving polarization of PIN-activating D6 protein kinase during root gravitropism

    Ivan Kulich, Julia Schmid ... Jiří Friml
    Negative Gravitropic Response of roots (NGRs), pivotal for root gravitropic bending, are indispensable for the gravity-induced translocation of D6 protein kinase, a key regulator of PIN3 auxin efflux carrier activity.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells

    Heidi Hehnly, David Canton ... John D Scott
    A protein kinase complex that is important for cell division is lost in testicular seminoma, which is a common cancer in men.