The hierarchy of entorhinal grid cell modules with constant scale ratios can self-organize through a new geometrically organized attractor mechanism.

Dementia-related tau pathology reduces speed encoding in the medial entorhinal cortex and is associated with reduced grid cell function, whilst head direction tuning remains intact.

The neural representation of position in the medial entorhinal cortex may be stabilized by synaptic connectivity across modules, which enforces coherent updates in their states.

A computational model for the formation of neural networks of grid cells in virtual bats suggests that the highly ordered networks presumed to support spatial navigation in two dimensions cannot be routinely established in three-dimensional space.

Mathematical modeling suggests that grid cells in the rodent brain use fundamental principles of number theory to maximize the efficiency of spatial mapping, enabling animals to accurately encode their location with as few neurons as possible.

Random fluctuations in neuronal firing may enable a single brain region, the medial entorhinal cortex, to perform distinct roles in cognition (by generating gamma waves) and spatial navigation (by producing a grid cell map).

When a familiar environment is reshaped, the grid cell spatial code is dynamically anchored to recently encountered boundaries and changes throughout exploration with the specific movement history of the navigator.

Computational modeling of the brain’s navigation system reveals that place cells can drive the formation of hexagonal patterns experimentally observed in grid cells activity.

Local human movement into mosquito habitats around forest edges intensifies interactions between pathogens, insects and people, increasing exposure risks to the zoonotic malaria Plasmodium knowlesi in Malaysian Borneo.

A large variety of spatial representations implied in rodent navigation could arise robustly and rapidly from inputs with a weak spatial structure, by an interaction of excitatory and inhibitory synaptic plasticity.