8,345 results found
    1. Cell Biology
    2. Computational and Systems Biology

    Quantifying absolute gene expression profiles reveals distinct regulation of central carbon metabolism genes in yeast

    Rosemary Yu, Egor Vorontsov ... Jens Nielsen
    Global gene expression control mechanisms are modeled using a large dataset consisting of absolute-quantitative proteomics, transcriptomics, and partial metabolomics of Saccharomyces cerevisiae at a wide range of growth conditions.
    1. Developmental Biology

    The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression

    Aynur Kaya-Çopur, Fabio Marchiano ... Frank Schnorrer
    Muscle fiber growth during development is controlled by the Hippo pathway that links the assembly state of the contractile sarcomeres with the transcriptional state of the sarcomeric genes.
    1. Cell Biology
    2. Developmental Biology

    Dpp controls growth and patterning in Drosophila wing precursors through distinct modes of action

    Pablo Sanchez Bosch, Ruta Ziukaite ... Jean-Paul Vincent
    Striped expression of Dpp in Drosophila wing precursors leads to graded signalling activity that positions wing veins and, in parallel, promotes growth in a gradient-independent manner by supplying signalling activity above a threshold.
    1. Cell Biology

    Spatial control of translation repression and polarized growth by conserved NDR kinase Orb6 and RNA-binding protein Sts5

    Illyce Nuñez, Marbelys Rodriguez Pino ... Fulvia Verde
    NDR kinase Orb6 prevents RNP granule assembly and translational repression by promoting Sts5 association with 14-3-3 protein Rad24 to spatially control polarized cell growth.
    1. Neuroscience

    Circulating transforming growth factor-β1 facilitates remyelination in the adult central nervous system

    Machika Hamaguchi, Rieko Muramatsu ... Toshihide Yamashita
    Although central nervous system (CNS) regeneration has been considered to be controlled by CNS microenvironment, CNS injury causes leading to leakage of circulating factors into CNS, which promotes CNS regeneration.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates

    Juliane Glaser, Julian Iranzo ... Deborah Bourc'his
    Zdbf2 is a paternally expressed gene that is mainly expressed in the hypothalamus and promotes appetite and body weight gain in neonates.
    1. Cancer Biology

    Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth

    Kashyap Dave, Inderpreet Sur ... Jussi Taipale
    A tumor-specific regulatory region has been identified upstream of the Myc oncogene.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Intestinal GCN2 controls Drosophila systemic growth in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNA operons

    Théodore Grenier, Jessika Consuegra ... François Leulier
    Bacterial ribosomal and transfer RNAs are symbiotic clues sensed by host general control nonderepressible 2 to support Drosophila systemic growth.
    1. Developmental Biology

    The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6

    Yun Qing, Feng Yin ... Duojia Pan
    Elucidating the molecular mechanism by which the Hippo signaling effector Yorkie (Yki) functions as a transcriptional coactivator in growth control reveals the importance of a histone-modifying enzyme for this process.
    1. Cell Biology
    2. Plant Biology

    Auxin regulates SNARE-dependent vacuolar morphology restricting cell size

    Christian Löfke, Kai Dünser ... Jürgen Kleine-Vehn
    Vacuolar morphologenesis correlates with cell size and is required for auxin-dependent inhibition of growth.

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