4,054 results found
    1. Neuroscience

    Filopodial dynamics and growth cone stabilization in Drosophila visual circuit development

    Mehmet Neset Özel et al.
    Long-term live imaging in intact developing Drosophila brains reveals a role for N-Cadherin-mediated fast filopodial dynamics and growth cone stabilization during neural circuit assembly.
    1. Cell Biology

    Mammalian cell growth dynamics in mitosis

    Teemu P Miettinen et al.
    High-resolution single-cell mass accumulation and protein synthesis rate measurements are used to quantify the extent, dynamics and consequences of animal cell growth in mitosis and cytokinesis.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency

    Maxim Greenberg et al.
    Three-dimensional chromatin architecture facilitates a promoter switch in order to ensure maintained expression of a gene involved in growth during embryonic stem cell differentiation.
    1. Cancer Biology
    2. Computational and Systems Biology

    Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes

    Rolando Ruiz-Vega et al.
    Spontaneous growth arrest of transformed melanocytes (resulting in benign “moles”) does not result from cell-autonomous oncogene-induced senescence, but can be explained by collective mechanisms used in normal tissue size control.
    1. Developmental Biology

    Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage

    Marketa Kaucka et al.
    The clonal oriented cell dynamics enables directional expansion and accurate scaling of sheet-like or rod-like cartilaginous elements and uncouples the mechanisms of elongation from thickness or diameter control.
    1. Physics of Living Systems

    Mechanics and kinetics of dynamic instability

    Thomas CT Michaels et al.
    A theoretical framework for the growth of microtubules quantifies the roles of geometry, mechanics, kinetics and randomness and provides a phase diagram for dynamic instability in these self-assembled polymers.
    1. Computational and Systems Biology

    Spatiotemporal establishment of dense bacterial colonies growing on hard agar

    Mya R Warren et al.
    A 3D model captures the growth and expansion dynamics of bacterial colonies, revealing distinct effects of surface tension, mechanical forces, and nutrients on the speed of radial and vertical expansion.
    1. Developmental Biology

    Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling

    Kenji Kamimoto et al.
    Clonal tracing in vivo and quantitative modeling in silico reveal a unique mode of tissue growth and structural remodeling of the biliary system, providing an insight into the cellular basis for robust liver regeneration.
    1. Cell Biology
    2. Physics of Living Systems

    Non-genetic inheritance restraint of cell-to-cell variation

    Harsh Vashistha et al.
    Quantitative measurement of epigenetic memory and inheritance dynamics.
    1. Physics of Living Systems
    2. Developmental Biology

    Unified quantitative characterization of epithelial tissue development

    Boris Guirao et al.
    A new approach measures the respective participations of elementary cell behaviors – such as cell division, intercalation, shape change and death – in the shaping of animal tissues.

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