63 results found
    1. Neuroscience

    An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence

    Silke Frahm et al.
    Local elimination of acetylcholine synthesis in habenular neurons demonstrates a key role for vesicular synergy and neurotransmitter co-release in nicotine dependence.
    1. Neuroscience

    Increased theta/alpha synchrony in the habenula-prefrontal network with negative emotional stimuli in human patients

    Yongzhi Huang et al.
    Increased theta/alpha band activities within the habenula area and the prefrontal cortex, as well as the increased synchrony between the two structures in the same frequency band can serve as an indicator for negative emotions in humans.
    1. Neuroscience

    GABAB receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals

    Pradeep Bhandari et al.
    The direct interaction of R-type Ca2+ channel Cav2.3 and GABAB receptor auxiliary subunits in the active zone of medial habenula terminals scales synaptic strength independent of GABAB receptor activation.
    1. Neuroscience

    Anatomical and single-cell transcriptional profiling of the murine habenular complex

    Michael L Wallace et al.
    Single-cell transcriptional profiling reveals distinct neuronal subtypes of the lateral habenula differentially target downstream neuronal subtypes in the ventral tegmental area and dorsal raphe nucleus.
    1. Neuroscience

    Valence-encoding in the lateral habenula arises from the entopeduncular region

    Hao Li et al.
    Lateral habenula neurons participate in motivated behavior via their activation by negative affective stimuli, a major source of which arises from the rostral entopeduncular nucleus.
    1. Neuroscience

    Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior

    Salvatore Lecca et al.
    Glutamatergic signaling from the lateral hypothalamus instructs lateral habenular neurons for encoding aversive external stimuli to subsequently guide escape behaviours.
    1. Developmental Biology
    2. Neuroscience

    Sox1a mediates the ability of the parapineal to impart habenular left-right asymmetry

    Ingrid Lekk et al.
    The sox1a gene is required for a small group on neurons on the left side of the brain to influence the generation and left-sided character of their future synaptic partners.
    1. Neuroscience

    Learning shapes the aversion and reward responses of lateral habenula neurons

    Daqing Wang et al.
    Neurons in the lateral habenula are activated by pain, bitterness and social defeat, and their responses are dynamically shaped by learning, suggesting a role in experience-dependent selection of behavioral actions to stressors.
    1. Neuroscience

    An excitatory lateral hypothalamic circuit orchestrating pain behaviors in mice

    Justin N Siemian et al.
    A small population of lateral hypothalamic neurons detects pain and can be activated to suppress pain-related behavioral adaptations and the unpleasantness associated with pain in mice.
    1. Neuroscience

    Experience, circuit dynamics, and forebrain recruitment in larval zebrafish prey capture

    Claire S Oldfield et al.
    Experience strengthens hunting in larval zebrafish by recruiting the forebrain to increase the prey-evoked activity in visual areas and trigger motor activity and prey capture.

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