The development of a transgenic zebrafish allows for cell-type-specific labeling of neuronal protein synthesis, enabling brain-wide visualization and quantification of protein synthesis and demonstrating region-specific increases following elevated brain activity.
Loss of function of the selective autophagy adaptor protein Alfy/Wdfy3 leads to profound wiring defects from the forebrain through to the spinal cord, highlighting the growing importance for macroautophagy in the developing brain.
Opioid sensitive neurons were identified using a traceless affinity labeling strategy to covalently label endogenous mu-opioid receptors with fluorescent compounds in living brain slices from wild type animals.
The anticipation of rewards turns out to have its own hedonic value, on top of that of the reward itself; a wide range of behavioral and neurophysiological data suggest that this anticipation is boosted by prediction errors.
Spontaneous and evoked patterns of neural activity in the larval zebrafish tectum become less similar over development, in contrast with a previous hypothesis for the computational role of spontaneous activity.