Joachim Linssen, Anthony Ermens ... Andre J van der Ven
Distinct haemocytometric parameters, including cell activation markers, combined in a prognostic score may support early identification of COVID-19 patients likely to deteriorate and thus may benefit from ICU admission.
Charlotte E Davies, Jessica E Thomas ... Christopher J Coates
Neither the presence nor the intensity of Hematodinium sp. parasitisation drives co-infection occurrence, severity, or diversity in the ecologically ubiquitous shore crab, Carcinus maenas.
Paul Capewell, Christelle Cren-Travaillé ... Annette MacLeod
African trypanosomes residing within the skin of infected humans represent an important yet overlooked transmissible parasite population that may thwart efforts to eliminate African sleeping sickness.
Laura Ferrer-Font, Palak Mehta ... Johannes U Mayer
A systematic optimization of intestinal digestion protocols allows for the isolation and high-dimensional flow cytometric analysis of intestinal immune cells during murine helminth infection.
Matthew Swire, Yuri Kotelevtsev ... Charles ffrench-Constant
Endothelin signalling, regulated by changes in neuronal activity associated with experience, influences the number of myelin sheaths formed by individual oligodendrocytes.
Richard J Lindsay, Michael J Kershaw ... Ivana Gudelj
Cooperation theory and a novel synthetic infection system provides a mechanistic understanding of why a seemingly successful disease management strategy can have devastating consequences for infected hosts.
Sara Silva Pereira, Mariana De Niz ... Luisa M Figueiredo
While Trypanosoma congolense is mostly known to cause a chronic wasting disease in animals, a new mouse model shows that acute cerebral trypanosomiasis is triggered by parasite sequestration and infiltration of T helper cells in the brain parenchyma.
Lewis Macdonald, Gillian C Taylor ... Andrew J Wood
Auxin-inducible degradation of CRISPR-tagged endogenous proteins in mice reveals cell-type-specific dependence on the mitotic chromosome condensation proteins.
Emma M Briggs, Catarina A Marques ... Keith R Matthews
Single-cell transcriptomics of cryopreserved parasites reveals extensive cyclic regulation of mRNA abundance by Trypanosoma brucei during the cell cycle.