Ayelet M Rosenberg, Shannon Rausser ... Martin Picard
A method to profile hair pigmentation patterns establishes a new approach for psychobiological studies and links metabolic changes to greying in humans.
Hedgehog-pathway activation in adjacent epithelial and stromal cells, but not in epithelial or stromal cells alone, enables the generation of functional de novo hair follicles in unwounded adult mouse skin.
Regional differences in activator and inhibitor signals alter hair cycle pace across mouse skin and produce unique fur renewal 'landscapes', with fastest renewal on the ventrum and slowest renewal on the ear pinnae.
An approach that allows scientists to identify regions of the genome that evolved faster in hairless mammals reveals candidate genetic mechanisms that gave rise to hairlessness.
Infectosomes enabling polar progression of infection threads in legume roots require the symbioisis-related RPG protein that functions as an organizer of these structures.
Studying the genomes of mammals with sparse hair covering identifies specific genes and regulatory regions responsible for the formation of hair and skin, some of which were previously unrecognized.
Computational modeling and molecular-biological analysis reveal the role of mechanical force and downstream Yap signaling in growth control during the development and regeneration of sensory epithelium of the inner ear.
Daine R Lesniak, Kara L Marshall ... Ellen A Lumpkin
Computer simulations show that the firing patterns of branched touch receptors can be set in part by the organization of their sensory endings in the skin.
Modulation of dermal adipocytes contributes to skin homeostasis and provides a promising new therapeutic strategy in the treatment of EGFRI-related skin disorders.