Nicholas J Hathaway, Isaac E Kim ... Jeffrey A Bailey
Sequence analyses show a pfhrp3 deletion mechanism involves duplication of chromosome 11 segment, which is normally removed via negative selection, and specific conditions are needed for spread including low transmission.
Toni de-Dios, Claudia Fontsere ... Carles Lalueza-Fox
The retrieval of whole genomes from museum specimens from the extinct Xerxes Blue butterfly shows signals of population decline that could be use to identify present-day endangered insect species.
Genetic association analyses in Latin American individuals revealed two additional loci associated with COVID-19 that were not previously found in other population groups.
Audrey Le Veve, Mathieu Genete ... Vincent Castric
By modulating the intensity of balancing selection at the S-locus, dominance between self-incompatibility alleles shapes the genetic load linked to each allele, creating inbreeding depression in some S-locus homozygotes.
Samuel Pattillo Smith, Gregory Darnell ... Lorin Crawford
Computational analysis reveals that additive summary statistics from genome-wide association studies can provide evidence of non-additive heritability in complex traits.
Mathew Thayer, Michael B Heskett ... Phillip A Yates
Molecular genetic analyses of ASARs reveals regulation of large-scale mammalian chromosome structure and function that includes long non-coding RNAs and nuclear RNA binding proteins as essential regulators of chromosome dynamics.
Comparative transcriptome analyses of human placenta reveal regulatory divergence between native highlanders and lowland immigrants living at high altitude, and a sex-biased pattern of genetic adaptation.
