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    1. Neuroscience

    Human foveal cone photoreceptor topography and its dependence on eye length

    Yiyi Wang, Nicolas Bensaid ... Austin Roorda
    Despite evidence of retinal stretching with eye growth, cone photoreceptor sampling density in the foveal center of humans actually increases with eye length.
    1. Neuroscience

    Retinal microvascular and neuronal pathologies probed in vivo by adaptive optical two-photon fluorescence microscopy

    Qinrong Zhang, Yuhan Yang ... Na Ji
    A properly designed two-photon fluorescence microscope allows high-resolution visualization of neurons and capillaries in healthy and diseased mouse retinas in vivo, while to visualize subcellular structures, adaptive optics is required to correct the eye-induced optical aberrations.
    1. Ecology
    2. Epidemiology and Global Health

    Point of View: The biospheric emergency calls for scientists to change tactics

    Fernando Racimo, Elia Valentini ... Julia B Halder
    The ever-worsening climate and ecological crises calls for life scientists to engage in advocacy and activism to galvanise governments and the public into action.
    1. Neuroscience

    Tactile sensory channels over-ruled by frequency decoding system that utilizes spike pattern regardless of receptor type

    Ingvars Birznieks, Sarah McIntyre ... Richard M Vickery
    Perception of vibrotactile frequency depends on the neural discharge pattern rather than the afferent type, thus requiring a reevaluation of the notion of Pacinian/non-Pacinian channels in tactile sensory system.
    1. Neuroscience
    2. Physics of Living Systems

    Random access parallel microscopy

    Mishal Ashraf, Sharika Mohanan ... Gil Bub
    A new imaging modality is described that can simultaneously record from several dishes without using robotics, which enables researchers to perform high-throughput, continuous measurements on biological samples.
    1. Neuroscience

    Perception in autism does not adhere to Weber’s law

    Bat-Sheva Hadad, Sivan Schwartz
    Perception in autism is sensitive to absolute rather than to relative metrics of the environment, encoding changes in the environment without calibrating the changes relative to reference stimulation.
    1. Cell Biology

    A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics

    Etai Sapoznik, Bo-Jui Chang ... Reto P Fiolka
    A novel single-objective light-sheet microscope with unparalleled spatiotemporal resolution enables imaging and optical manipulation of diverse biological specimens and processes.
    1. Neuroscience

    Neural adaptation to the eye’s optics through phase compensation

    Antoine Barbot, John T Pirog ... Geunyoung Yoon
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation

    Steven Henikoff, Jorja G Henikoff ... Kami Ahmad
    A simple modification of CUT&Tag chromatin profiling method provides high-quality chromatin accessibility maps and indicates that 'open' chromatin results from a transcription-coupled process at promoters and enhancers.
    1. Neuroscience
    2. Evolutionary Biology

    Investments in photoreceptors compete with investments in optics to determine eye design

    Francisco JH Heras, Simon B Laughlin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid