97 results found
    1. Cell Biology

    Impaired mRNA splicing and proteostasis in preadipocytes in obesity-related metabolic disease

    Julia Sánchez-Ceinos et al.
    Alternative splicing and the endoplasmic reticulum (ER)-associated protein degradation (ERAD) system represent essential, fat depot-specific components of the adipogenesis that are altered in preadipocytes from obese individuals with metabolic disease.
    1. Neuroscience

    Conserved visual capacity of rats under red light

    Nader Nikbakht, Mathew E Diamond
    Psychometric measures reveal that, contrary to common assumption, rats have good visual form discrimination capacity under red and even far-red illumination.
  1. Equity, Diversity and Inclusion: Alternative strategies for closing the award gap between white and minority ethnic students

    Louise Cramer
    An analysis of the grades awarded to cell biology students at University College London suggests that exams may contribute more to the award gap than coursework in this subject.
    1. Neuroscience

    Increased influence of prior choices on perceptual decisions in autism

    Helen Feigin et al.
    Perceptual decisions are influenced by preceding choices to a larger extent in individuals with autism spectrum disorder, such that they demonstrate a greater consistency bias.
    1. Genetics and Genomics
    2. Plant Biology

    Genomic basis for drought resistance in European beech forests threatened by climate change

    Markus Pfenninger et al.
    European beech harbours substantial genetic variation at genomic loci associated with drought resistance and newly identified loci can help to accelerate and monitor adaptation to climate change.
    1. Epidemiology and Global Health
    2. Medicine

    Do wealth and inequality associate with health in a small-scale subsistence society?

    Adrian V Jaeggi et al.
    Socio-economic hierarchies may be bad for health, even among people living in a relatively traditional, small-scale society in the Bolivian Amazon.
    1. Neuroscience

    Spatially displaced excitation contributes to the encoding of interrupted motion by a retinal direction-selective circuit

    Jennifer Ding et al.
    The direction-selective circuit in the retina adjusts the contributions of excitatory and inhibitory mechanisms under different stimulus conditions to generate context-dependent neural representations of visual features.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Allosteric conformational ensembles have unlimited capacity for integrating information

    John W Biddle et al.
    The effective higher-order binding cooperativities arising from an ensemble of dynamically interchanging conformations are identified and shown to fully describe integration of binding information at thermodynamic equilibrium.
    1. Neuroscience

    Perturbation of amygdala-cortical projections reduces ensemble coherence of palatability coding in gustatory cortex

    Jian-You Lin et al.
    Blocking input from basolateral amygdala to gustatory cortex (GC) severely reduces the coherence of GC ensemble activity, which negatively affects epochal dynamics involved in driving palatability-driven consumption.
    1. Immunology and Inflammation
    2. Medicine

    Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics

    Juana Serrano-Lopez et al.
    Endotoxemia recruits fast-acting anti-inflammatory innate myeloid progenitors from bone marrow into regional lymphatics through release of pre-formed Ccl19 secondary to NF-κB-independent, Traf6/IκB kinase-dependent signaling.

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