Joshua S Talboom, Asta Håberg ... Matthew J Huentelman
An internet-based cohort study of paired associate learning shows that a first-degree family history of dementia is associated with lowered performance, an effect modified by apolipoprotein E genotype and diabetes.
Ursula Dalrymple, Ewan Cameron ... Peter W Gething
Fevers amongst African children are often assumed to be caused by a malaria infection, but here it is estimated that the majority of fevers amongst African children, including those with a patent malaria infection, are due to infections with diseases other than malaria.
Christopher S Williams, W Kimryn Rathmell ... Mone Zaidi
Challenges faced by the declining global workforce of young physician-scientists are highlighted, and a unified view on how to revive and reinvigorate this critical pool of dual-trained physicians worldwide is provided.
Nationally-representative verbal autopsies can be linked to seasonal patterns, clinical syndromes, and climate regions to describe novel insights regarding the microbiologic etiologies of childhood pneumonia and diarrhea in India.
Fruit flies have special neurons in their pharynx with ionotropic receptors to prevent consuming too much salt, which was confirmed using a variety of behavioral and physiological assays.
Fanny Janssen, Anastasios Bardoutsos ... Joop De Beer
Accounting for the impact of smoking, obesity, and alcohol on past mortality trends, we project, compared to common practice, longer individual lifespans and more elderly in society for the future.
The new early warning system, COEWS, will improve the early identification and management of high-risk COVID-19 patients compared to the widely used NEWS2 by using easy-to-obtain clinical parameters that have been externally validated in a diverse multicontinental cohort of patients.
Nerve tracing and behavioral studies in tumor-bearing mice together with transcriptional and functional analysis reveal cancer-induced central and peripheral neuronal alterations that influence behavior.