54 results found
    1. Neuroscience
    2. Physics of Living Systems

    Tuning of feedforward control enables stable muscle force-length dynamics after loss of autogenic proprioceptive feedback

    Joanne C Gordon et al.
    Running guinea fowl maintain stable running after loss of the stretch reflex in a major ankle extensor muscle, by increasing feedforward muscle activation to maintain ankle stiffness and work output.
    1. Genetics and Genomics

    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Timothy R Fallon et al.
    The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Motility precedes egress of malaria parasites from oocysts

    Dennis Klug, Friedrich Frischknecht
    A surface protein triggers intra-oocyst motility of Plasmodium sporozoites to ensure parasite egress from oocysts.
    1. Neuroscience

    Motoneurons regulate the central pattern generator during drug-induced locomotor-like activity in the neonatal mouse

    Melanie Falgairolle et al.
    Motoneuron activity provides feedback to the spinal network responsible for generating locomotion in the developing mouse spinal cord.
    1. Cancer Biology
    2. Cell Biology

    Chimeric antigen receptors that trigger phagocytosis

    Meghan A Morrissey et al.
    A family of engineered immune receptors trigger internalization of cancer cells and antigen-coated targets.
    1. Computational and Systems Biology
    2. Neuroscience

    Visuomotor learning from postdictive motor error

    Jana Masselink, Markus Lappe
    Visual, motor, and forward model gains learn from a postdictive update of space to keep perception and saccadic motor function aligned.
    1. Cell Biology
    2. Neuroscience

    The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains

    Vladimir Zhemkov et al.
    Signaling function of sigma 1 receptor is related to its ability to organize cholesterol-enriched microdomains in the endoplasmic reticulum membrane.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The architecture of EMC reveals a path for membrane protein insertion

    John P O'Donnell et al.
    Structural and biochemical analysis of an abundant and conserved protein complex called EMC shows how it is likely to insert nascent membrane proteins into the endoplasmic reticulum membrane.
    1. Evolutionary Biology

    Phenotypic plasticity as a mechanism of cave colonization and adaptation

    Helena Bilandžija et al.
    Astyanax mexicanus surface-dwelling fish exposed to complete darkness develop many traits resembling cavefish adaptations by phenotypic plasticity in a single generation.
    1. Developmental Biology
    2. Genetics and Genomics

    Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism

    Samuel Andrew Malone et al.
    Mouse in vivo and in vitro analysis and human genetic screening highlight the role of anti-Müllerian hormone (AMH) signaling in GnRH neuronal development and function, and identify mutations in AMH and AMHR2 in CHH patients.

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