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Short-term interventions, including intermittent fasting, boosting cellular energy, and promoting beneficial gut bacteria, rejuvenate osteoprogenitors in aged animals and, when combined with localized Wnt, restore youthful bone healing.

If CHIP and mLOY do not significantly contribute to inflammation, atherosclerosis or myocardial infarction risk independently, CHIP may increase the risk of MI in men who do not carry mLOY.

A successful innate granuloma requires CCR2 to organize the macrophage ring, and without CCR2, mice succumb to Chromobacterium violaceum infection.

DKK2 is crucial for the development of lysozyme-expressing cancer cells with Paneth cell characteristics necessary for liver metastasized colon cancer growth.

Transplanted human iPSC-derived microglial cells with immune responses and phagocytic abilities integrate and occupy native microglial cell space and functionally respond to retinal injuries.

Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26^-CD35⁺ healthy stem cells and CD26⁺CD35^- CML stem cells, and how the ratio between these impacts TKI response.

Pkc53E kinase-mediated downregulation of CSL/Su(H) activity is a direct molecular response to parasitoid wasp infestation in Drosophila, allowing the differentiation of encapsulation-active lamellocytes, thereby ensuring an appropriate immune defense.