Browse the search results

Page 2 of 38
    1. Stem Cells and Regenerative Medicine

    Rejuvenating aged osteoprogenitors for bone repair

    Joshua Reeves, Pierre Tournier ... Shukry J Habib
    Short-term interventions, including intermittent fasting, boosting cellular energy, and promoting beneficial gut bacteria, rejuvenate osteoprogenitors in aged animals and, when combined with localized Wnt, restore youthful bone healing.
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associations

    Luke J Dillard, Gina M Calabrese ... Charles R Farber
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cancer Biology

    Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden

    Hyungtai Sim, Hyun Jung Park ... Murim Choi
    In metastatic NSCLC patients, CHIP showed minimal impact on immunotherapy response but was more prevalent and associated with inflammatory pathways in myeloid cells, particularly in lung squamous cell carcinoma.
    1. Stem Cells and Regenerative Medicine

    Dynamic tracking of native precursors in adult mice

    Suying Liu, Sarah E Adams ... Peter Kurre
    A revised analytical framework grounded in the principle of binomial distribution captures the full clonality and dynamic shifts of hematopoiesis throughout ontogeny.
    1. Microbiology and Infectious Disease

    Telomerase RNA component knockout exacerbates Staphylococcus aureus pneumonia by extensive inflammation and dysfunction of T cells

    Yasmina Reisser, Franziska Hornung ... Stefanie Deinhardt-Emmer
    Knockout of Terc impedes effective immune defense against bacterial lung infections in mice, exacerbating disease course and revealing the critical function of Terc in pulmonary immunity.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity

    Khund Sayeed, Sreeja Parameswaran ... Matthew T Weirauch
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest

    Tim Casey-Clyde, S John Liu ... David R Raleigh
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Medicine

    Estimating bone marrow adiposity from head MRI and identifying its genetic architecture

    Tobias Kaufmann, Pål Marius Bjørnstad ... Timothy Hughes
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

    Fan Zhang, Yuan Wang ... Xianpeng Ge
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    TET2 contributes to gluconeogenesis and pathology of type 2 diabetes

    Xinchao Zhang, Hongchen Li ... Yanping Xu
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
Newer Older