High glucose levels promote CTSL maturation and translocation from the endoplasmic reticulum to the lysosome via the ER-Golgi-lysosome axis.

Incompatibilities between the viral replication machinery and orthologs of the essential host factor cyclophilin A (CypA) contribute to the narrow host range of hepatitis C virus.

Very frequent viral kinetics in liver transplant patients reveals that the liver is not only the source of hepatitis C virus (HCV) production, but also plays a major role in extracellular HCV clearance.

Duck Hepatitis B core protein forms capsids with a slowly folding extension domain which folding competence is important for viral replication.

Loss of function of membrane-bound O-acyltransferase 7 (MBOAT7), but not transmembrane channel-like 4 (TMC4), promotes hepatic steatosis.

A small surface protein regulates gliding motility and host cell invasion by the sporozoite stage of the malaria parasite.

A novel strategy to activate the WNT pathway in a cell type selective manner by linking designer ligands with target cell specific bridging receptors.

Host CD81 and Scavenger Receptor BI operate independently to mediate invasion of hepatocytes by different species of Plasmodium sporozoites, which use the parasite protein P36 as a key determinant of the entry route.

L. interrogans utilizes endocytic recycling and vesicular transport systems for transcytosis across endothelial or epithelial barrier in blood vessels or renal tubules, which contributes to spreading and transmission of leptospirosis.