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    1. Neuroscience

    Sex-specific behavioral and thalamo-accumbal circuit adaptations after oxycodone abstinence

    Yanaira Alonso-Caraballo, Yan Li ... Elena H Chartoff
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    Determining the effects of paternal obesity on sperm chromatin at histone H3 lysine 4 tri-methylation in relation to the placental transcriptome and cellular composition

    Anne-Sophie Pepin, Patrycja A Jazwiec ... Sarah Kimmins
    Epigenomic and transcriptomic analysis reveals that paternal obesity influences sperm histone H3 lysine 4 tri-methylation enrichment and placenta gene expression, which in turn negatively impact its development and function in a manner that may contribute to metabolic disease in offspring.
    1. Genetics and Genomics
    2. Evolutionary Biology

    The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle

    Torsten Günther, Jacob Chisausky ... Cristina Valdiosera
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Physics of Living Systems

    Toward Stable Replication of Genomic Information in Pools of RNA Molecules

    Ludwig Burger, Ulrich Gerland
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Synaptic input architecture of visual cortical neurons revealed by large-scale synapse imaging without backpropagating action potentials

    Satoru Kondo, Kohei Kikuta, Kenichi Ohki
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Developmental Biology

    Diversity in Notch ligand-receptor signaling interactions

    Rachael Kuintzle, Leah A Santat, Michael B Elowitz
    The Notch signaling pathway can use its various ligands, receptors, and Fringe proteins to generate diverse intra- and intercellular signaling behaviors.
    1. Cell Biology
    2. Evolutionary Biology

    Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

    P Richard J Yulo, Nicolas Desprat ... Heather L Hendrickson
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology

    Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption

    John Yong, Jacqueline E Villalta ... Calvin H Jan
    Genome-wide CRISPRi screens and proteome profiling of lysosomes link lipid dysregulation to ESCRT disruption and proteostasis defect.
    1. Cell Biology

    Characterization of the cellular components of mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells regulating lymphatic contractions

    Scott D Zawieja, Grace A Pea ... Michael J Davis
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Neuroscience

    Circadian control of a sex-specific behaviour in Drosophila

    Sabrina Riva, M Fernanda Ceriani ... D Lorena Franco
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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