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    1. Developmental Biology

    The vascular niche controls Drosophila hematopoiesis via fibroblast growth factor signaling

    Manon Destalminil-Letourneau, Ismaël Morin-Poulard ... Michele Crozatier
    Two niches contribute to the control of Drosophila blood cell homeostasis through their differential regulation of hematopoietic progenitors.
    1. Immunology and Inflammation

    The Extra-Islet Pancreas Supports Autoimmunity in Human Type 1 Diabetes

    GL Barlow, CM Schürch ... PL Bollyky
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Physics of Living Systems

    Toward Stable Replication of Genomic Information in Pools of RNA Molecules

    Ludwig Burger, Ulrich Gerland
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology
    2. Chromosomes and Gene Expression

    High-precision mapping of nuclear pore-chromatin interactions reveals new principles of genome organization at the nuclear envelope

    Swati Tyagi, Juliana S. Capitanio ... Martin W. Hetzer
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology

    Novel Mechanism for Tubular Injury in Nephropathic Cystinosis

    Swastika Sur, Maggie Kerwin ... Minnie M Sarwal
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cancer Biology
    2. Cell Biology

    Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells

    Alejandro La Greca, Nicolás Bellora ... Patricia Saragüeta
    Binding of progesterone receptor and transcription factor PAX2 to pre-assembled permissive chromatin compartments regulates endometrial cancer gene expression under estrogenic conditions.
    1. Developmental Biology

    Neuron hemilineages provide the functional ground plan for the Drosophila ventral nervous system

    Robin M Harris, Barret D Pfeiffer ... James W Truman
    Hemilineages link neuronal stem cells to behavioral functions by providing a conserved ground plan of neuronal types that evolution then uses to sculpt different types of walking and flight behaviors.
    1. Genetics and Genomics
    2. Evolutionary Biology

    The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle

    Torsten Günther, Jacob Chisausky ... Cristina Valdiosera
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Characterization of direct Purkinje cell outputs to the brainstem

    Christopher H Chen, Zhiyi Yao ... Wade G Regehr
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Neuroscience

    Photoreceptor loss does not recruit neutrophils despite strong microglial activation

    Derek Power, Justin Elstrott, Jesse Schallek
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete