1,519 results found
    1. Neuroscience

    Are single-peaked tuning curves tuned for speed rather than accuracy?

    Movitz Lenninger, Mikael Skoglund ... Arvind Kumar
    Single-peaked tuning curves found in early sensory areas are more optimized for quick decoding than accuracy, while multi-peaked tuning curves (e.g. grid cells) give higher accuracy but only at longer time scales.
    1. Neuroscience

    Transformation of valence signaling in a mouse striatopallidal circuit

    Donghyung Lee, Nathan Lau ... Cory M Root
    The representation of odor transforms from high dimensional, population level encoding of valence and identity in the OT, to a low dimensional representation of valence in the VP.
    1. Neuroscience

    Nonlinear circuits for naturalistic visual motion estimation

    James E Fitzgerald, Damon A Clark
    New computational models provide insights into how the insect brain estimates the speed and direction of movement.
    1. Neuroscience

    Network dynamics underlying OFF responses in the auditory cortex

    Giulio Bondanelli, Thomas Deneux ... Srdjan Ostojic
    Computational modeling demonstrates that population dynamics of neural calcium activity following stimulus offset are consistent with a network mechanism based on recurrent interactions.
    1. Neuroscience

    Population coupling predicts the plasticity of stimulus responses in cortical circuits

    Yann Sweeney, Claudia Clopath
    Networks simulations and in vivo imaging suggest a stable backbone of stimulus representation formed by neurons with low population coupling, alongside a flexible substrate of neurons with high population coupling.
    1. Computational and Systems Biology
    2. Neuroscience

    A functional model of adult dentate gyrus neurogenesis

    Olivia Gozel, Wulfram Gerstner
    The GABA input switching from excitatory to inhibitory during maturation of adult-born dentate granule cells is crucial for their integration into the preexisting circuit.
    1. Neuroscience

    Unsupervised discovery of temporal sequences in high-dimensional datasets, with applications to neuroscience

    Emily L Mackevicius, Andrew H Bahle ... Michale S Fee
    Building on simple unsupervised matrix factorization techniques, the seqNMF algorithm successfully recovers neural sequences in a wide range of simulated and real datasets.
    1. Neuroscience

    Inconsistencies between human and macaque lesion data can be resolved with a stimulus-computable model of the ventral visual stream

    Tyler Bonnen, Mark AG Eldridge
    A 'stimulus-computable' modeling approach resolves apparent inconsistencies between human and monkey lesion data, implicating perirhinal cortex in visual object perception.
    1. Neuroscience

    A chromatic feature detector in the retina signals visual context changes

    Larissa Höfling, Klaudia P Szatko ... Thomas Euler
    A modelling-based analysis reveals a novel type of selectivity for chromatic contrast in a mouse retinal ganglion cell type, and experimental evidence shows that this feature makes this cell type well suited for detecting behaviourally relevant changes in visual context.
    1. Computational and Systems Biology
    2. Neuroscience

    Task-dependent optimal representations for cerebellar learning

    Marjorie Xie, Samuel P Muscinelli ... Ashok Litwin-Kumar
    Classical theoretical approaches to studying the cerebellar cortex are generalized to a broader set of learning tasks, revealing that the optimal value for the sparsity of granule cell activity is task-dependent.

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