Browse the search results

Page 2 of 10
    1. Developmental Biology
    2. Neuroscience

    Expansion microscopy of C. elegans

    Chih-Chieh (Jay) Yu et al.
    Fixed, intact animals of C. elegans can be physically expanded with high isotropy, to enable super-resolved imaging of general proteins and nucleic acids throughout the organism, on conventional microscopes.
    1. Physics of Living Systems
    2. Cell Biology

    The axonal actin-spectrin lattice acts as a tension buffering shock absorber

    Sushil Dubey et al.
    A linear array of spectrin tetramers imparts mechanical stability to axons by allowing spectrin domains to unfold reversibly when an axon is stretched, thereby acting as tension buffers.
    1. Neuroscience

    A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain

    Naoyuki Matsumoto et al.
    Sonic hedgehog signaling is crucial for the self-renewal of outer radial glial cells and gyrus formation of the cerebral cortex in gyrencephalic mammals.
    1. Structural Biology and Molecular Biophysics

    Human RPA activates BLM’s bidirectional DNA unwinding from a nick

    Zhenheng Qin et al.
    hRPA permits the BLM helicase to bidirectionally unwind DNA from a nick which could potentially facilitate its function switching in DNA repair and promote end resection in homologous recombination.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    ParB spreading on DNA requires cytidine triphosphate in vitro

    Adam SB Jalal et al.
    A biochemical reconstitution shows that the accumulation of Caulobacter crescentus ParB on DNA requires cytidine triphosphate and a closed DNA substrate in vitro.
    1. Immunology and Inflammation

    High-dimensional analysis of intestinal immune cells during helminth infection

    Laura Ferrer-Font et al.
    A systematic optimization of intestinal digestion protocols allows for the isolation and high-dimensional flow cytometric analysis of intestinal immune cells during murine helminth infection.
    1. Cell Biology
    2. Plant Biology

    Imaging plant germline differentiation within Arabidopsis flowers by light sheet microscopy

    Sona Valuchova et al.
    Light sheet microscopy was used to establish a method for live imaging of cellular events within Arabidopsis flower and for constructing a 3D model of flower at subcellular resolution.
    1. Structural Biology and Molecular Biophysics

    HIV restriction factor APOBEC3G binds in multiple steps and conformations to search and deaminate single-stranded DNA

    Michael Morse et al.
    APOBEC3G, an anti-viral protein with the capability to inhibit HiV-1 infectivity, binds single stranded DNA in multiple physical conformations, enabling complex interactions that allow APOBEC3G to perform multiple diverse functions.
    1. Cell Biology
    2. Developmental Biology

    Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth

    Steve Dos-Santos Carvalho et al.
    The core PCP protein acts as a internal brake to neuronal outgrowth.
    1. Developmental Biology
    2. Neuroscience

    Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis

    Youngsik Woo et al.
    Sequential phosphorylation of NDEL1 Ser336/Ser332 by DYRK2 and GSK3β is a novel regulatory step for actin dynamics that contributes to the neurite outgrowth and neuronal arborization in the developing brain.