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    1. Neuroscience

    An adaptable, reusable, and light implant for chronic Neuropixels probes

    Célian Bimbard, Flóra Takács ... Philip Coen
    The Apollo implant, an open-source device tested in eight laboratories, can be used to reversibly implant Neuropixels probes and track the activity of populations of neurons across days.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing their formation in Caenorhabditis elegans

    Bhumil Patel, Maryke Grobler ... Needhi Bhalla
    By regulating the chromosome axis component and meiotic HORMAD, HIM-3, the conserved AAA-ATPase PCH-2 controls the number and distribution of meiotic recombination events.
    1. Neuroscience

    A deep learning framework for automated and generalized synaptic event analysis

    Philipp S O’Neill, Martín Baccino-Calace ... Igor Delvendahl
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

    Gülnihal Kavaklıoğlu, Alexandra Podhornik ... Christian Seiser
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Physics of Living Systems

    Stability vs flexibility: reshaping archaeal membranes in silico

    Miguel Amaral, Felix Frey ... Anđela Šarić
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    PRMT1-Mediated Metabolic Reprogramming Promotes Leukemogenesis

    Hairui Su, Yong Sun ... Xinyang Zhao
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland

    Gabriel Magno de Freitas Almeida, Iker Arriaga ... Lotta-Riina Sundberg
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    2-oxoglutarate triggers assembly of active dodecameric Methanosarcina mazei glutamine synthetase

    Eva Herdering, Tristan Reif-Trauttmansdorff ... Ruth A Schmitz
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability

    Joshua D Garcia, Chenyu Wang ... Kevin J Bender
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling