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Synchronous recording of skin deformations at the contact with a transparent surface and of tactile afferents from the fingertip reveals that afferents signal incipient slip.

Genome-wide mapping of heteroduplex DNA (a recombination intermediate) formed during mitotic recombination in yeast demonstrates that the "classical" model of double-strand DNA break repair is inadequate to explain several aspects of mitotic recombination.

New hybrid structure determination methods leveraging the inherent biophysical properties of a macromolecule through molecular dynamics simulations provide accurate and cost-efficient ways of achieving atomic structures from high resolution cryo-electron density maps.

A fully automated high-resolution in vivo screening platform for zebrafish was implemented and used to identify novel compounds that regulate oligodendrocyte lineage progression.

Micropatterned differentiation of human ESCs generates gastrulation cell types – germ layers, extraembryonic, and primordial germ cells with primate characteristics – that show conserved sorting behaviors when dissociated and reseeded as single-cell mixture.

High-resolution blood oxygen level-dependent functional magnetic resonance imaging enables brain-wide mapping of activated regions during sensory stimulation in awake mice, including associated areas, for high-order sensory processing including anticipation responses.

Microtubule attachment fundamentally modifies kinesin's behavior by triggering a ‘clamshell’ opening of the nucleotide cleft, subsequently reversed by ATP binding, that couples to cargo translocation.

Partial-volume effects were found to be the current limit to imaging pial arteries with MRI, not their slow blood flow, and therefore advanced acquisition techniques achieving resolutions below 200 µm in vivo provide a more complete picture of these vessels.

2D template matching enables a streamlined single-particle cryogenic electron microscopy workflow that can be used to discover new high-resolution structural features in molecules and complexes, such as bound ligands and drugs.

Spatial genomics reveals the mode of evolution of a tumour based on the positions of mutations in high-resolution samples.