Higher-order assembly enables and links pathogen recognition and downstream steps in the TRIM5-mediated anti-HIV response.

Experiments in ex-germ-free mice establish a measurable effect of colonization history on gut microbiota assembly, illuminating a potential cause for the high levels of unexplained individuality in host-associated microbial communities.

The scanning-assisted clustering mechanism of IFI16 not only allows efficient assembly on exposed foreign-dsDNA, but also suppresses the engagement of chromatinized self-dsDNA.

Structural insights show how RNA chaperones cooperate to recognise defined target transcripts and suppress gene expression.

Structural and functional approaches unambiguously revealed physiologically relevant lateral interactions between FtsZ protofilaments.

As the function of membrane proteins is often influenced by its membrane environment the presented combinatorial approach is of great value for the investigation of membrane protein complexes in natural or even manipulated lipid bilayers.

The genome sequence of Trichoplusia ni enables the use of this widespread lepidopteran pest as a model for both the study of small RNA pathways and insecticide resistance.

Nucleation, elasticity theory, and simulations were combined to construct a general phase diagram that elucidates the conditions for successful viral assembly and the key factors to prevent it.

Cells are able to control the actin network length and steering by adjusting geometric, structural, or biochemical parameters such as ADF/Cofilin and actin concentrations, and network width.

Rigorous reanalysis of single-molecule data yields evidence for energy expenditure in the interaction of transcription factors on DNA.