De novo-generated small proteins can cause deattenuation of an amino acid biosynthetic operon by direct protein–RNA interactions.

Comparative phylogenomic analyses based on a new reference-quality human Ascaris genome assembly reveals a pig/human interbred species complex with implications for Ascaris control worldwide.

Parasite life cycles may be more flexible than traditionally thought, potentially allowing single-cell infections of insect vectors and transmission between hosts even at very low parasite densities.

A new cellular transport mechanism splits the substrate and separately translocates its fragments to achieve selectivity.

The structure of the mechanosensitive channel MscS embedded in a lipid bilayer redefines the nature, location and importance of lipid–protein interactions in the gating of mechanosensitive channels.

Caught in a system eager for success stories, a PhD student from an underrepresented background learns how to balance his challenges in the lab with his desire to serve his community.

Trial-by-trial analysis of neuronal activity in monkeys performing a decision-making task reveals the neural correlates of behaviours including wavering, hesitation and sudden changes of mind.

Bacterial ribosomal and transfer RNAs are symbiotic clues sensed by host general control nonderepressible 2 to support Drosophila systemic growth.

After many professional twists and turns, a researcher reconsiders what it means to ‘make it’ in academia.

Carboxysomes, the carbon-fixation machinery of cyanobacteria, are equidistantly-positioned by dynamic gradients of the protein McdA on the nucleoid that emerge through interaction with a previously unidentified carboxysome factor, McdB.