A distinctive novel mechanism of ephrin-A/EphA signaling modulation in retinal growth cones ensures concurrent quantitative accuracy and adaptability of topographic hardwiring.
Direct observation of RNA Polymerase II transcription through a single nucleosome at near basepair resolution suggests a mechanism for selective control of gene expression.
Retinal ephrin-As gradients provide positional information, through retino-collicular map in the superior colliculus, for topographic alignment of cortico-collicular projections.
An all-optical 3D two-photon imaging and photostimulation platform was demonstrated, with the capability to precisely stimulate a large group of cells in mice cortex in vivo with low laser power.
The transmembrane shape of the F1Fo ATP synthase monomer provides the molecular basis of high curvature at the ridges of mammalian mitochondrial cristae.
A novel neural mechanism for precise, unbiased estimation of time intervals in the thalamus of electric fish is likely used for computing distance between object encounters.
A retinotopic proto-organization present at birth provides the infrastructure for the subsequent development of visual cortex that commences at the onset of visual experience.
Chromosome segregation in male spermatocytes exhibits anaphase A without shortening of autosome-associated microtubules and partitioning of an unpaired X chromosome that is initiated by an imbalance of attached kinetochore microtubules.