338 results found
    1. Neuroscience

    The nematode worm C. elegans chooses between bacterial foods as if maximizing economic utility

    Abraham Katzen, Hui-Kuan Chung ... Shawn R Lockery
    A worm with a nervous system of only 302 neurons satisfies the necessary and sufficient conditions for value-based decision making.
    1. Neuroscience

    A neurotransmitter atlas of C. elegans males and hermaphrodites

    Chen Wang, Berta Vidal ... Oliver Hobert
    Expression pattern analysis of neurotransmitter synthesis, secretion, and reuptake machinery reveals animal-wide usage of neurotransmitters in both sexes of Caenorhabditis elegans.
    1. Developmental Biology

    Marcks and Marcks-like 1 proteins promote spinal cord development and regeneration in Xenopus

    Mohamed El Amri, Abhay Pandit, Gerhard Schlosser
    Marcks and Marcks-like 1 proteins are required for normal neurite formation and proliferation of neuro-glial progenitors during development and regeneration of the Xenopus spinal cord implicating these proteins as critical new factors for spinal cord development and regeneration.
    1. Developmental Biology
    2. Genetics and Genomics

    Transcriptional control of compartmental boundary positioning during Drosophila wing development

    Gustavo Aguilar, Michèle Sickmann ... Martin Müller
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cancer Biology

    Use of signals of positive and negative selection to distinguish cancer genes and passenger genes

    László Bányai, Maria Trexler ... László Patthy
    In contrast with earlier conclusions, negative selection has a major role in cancer evolution.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes

    Amelie A Raz, Gabriela S Vida ... Margaret T Fuller
    Single nucleus and single cell RNA-seq data uncover novel transcriptomic perspectives in Drosophila testis biology and provide access to user-friendly tools for further scientific discovery in the field.
    1. Computational and Systems Biology

    DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics

    Vivian Tam, Peikai Chen ... Danny Chan
    Deep and comprehensive proteomic resource of human intervertebral disc at high spatial resolution with a methodological flow reveals new insights in disc homeostasis and degeneration.
    1. Plant Biology

    Fluctuations of the transcription factor ATML1 generate the pattern of giant cells in the Arabidopsis sepal

    Heather M Meyer, José Teles ... Adrienne H K Roeder
    Fluctuations of a transcription factor that coincide with the G2 phase of the cell cycle pattern two interspersed cell fates in a multicellular system.
    1. Evolutionary Biology
    2. Genetics and Genomics

    GENESPACE tracks regions of interest and gene copy number variation across multiple genomes

    John T Lovell, Avinash Sreedasyam ... Jeremy Schmutz
    GENESPACE lets users track related chromosomal sequences across multiple reference genomes.
    1. Neuroscience

    Increasing adult-born neurons protects mice from epilepsy

    Swati Jain, John J LaFrancois ... Helen E Scharfman
    Increasing adult-born neurons in the dentate gyrus reduces neuronal loss and chronic seizures in female mice using a mouse model of temporal lobe epilepsy.

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