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1,983 results found
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis

    Ritu Gupta et al.
    The role of an amino acid-dependent tRNA modification as a nutrient sensor and regulator of metabolic homeostasis has been discovered.
    1. Computational and Systems Biology
    2. Neuroscience

    Regulation of sleep homeostasis by sexual arousal

    Esteban J Beckwith et al.
    Sexual arousal, exposure to aphrodisiac pheromones, or mere activation of peripheral pheromone-sensing neurons can modulate sleep homeostasis and are able to counteract the effects of sleep deprivation in Drosophila.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Myogenin is an essential regulator of adult myofibre growth and muscle stem cell homeostasis

    Massimo Ganassi et al.
    Cellular and molecular analyses reveal how Myogenin controls muscle stem cell quiescence and growth of adult muscle fibres.
    1. Stem Cells and Regenerative Medicine

    Regulation of stem/progenitor cell maintenance by BMP5 in prostate homeostasis and cancer initiation

    Mathieu Tremblay et al.
    Gata3 loss in prostate basal stem/progenitor cells upregulates BMP5 which is necessary and sufficient to sustain full self-renewal potential and its inhibition significantly delays both prostate and skin tumor progression.
    1. Neuroscience

    Self-organization of modular network architecture by activity-dependent neuronal migration and outgrowth

    Samora Okujeni, Ulrich Egert
    Activity-dependent neurite outgrowth and neuronal migration interact to shape modular mesoscale network architecture by homeostatic self-organization.
    1. Neuroscience

    Homeostatic reinforcement learning for integrating reward collection and physiological stability

    Mehdi Keramati, Boris Gutkin
    A mathematical model built around the assumption that the desire to maintain internal homeostasis drives the behavior of animals, by affecting their learning processes, can explain many real-world behaviors, including some that might otherwise appear irrational.
    1. Microbiology and Infectious Disease

    A single regulator NrtR controls bacterial NAD+ homeostasis via its acetylation

    Rongsui Gao et al.
    Functional definition of NrtR and the discovery of its acetylation represents a first paradigm for linking protein acetylation to bacterial central NAD+ metabolism.
    1. Neuroscience

    Differential regulation of the Drosophila sleep homeostat by circadian and arousal inputs

    Jinfei D Ni et al.
    Functional imaging and circuit mapping in the Drosophila brain identifies neuropils where sleep-promoting and arousal-promoting neuronal networks converge.
    1. Developmental Biology

    Adrb2 controls glucose homeostasis by developmental regulation of pancreatic islet vasculature

    Alexis M Ceasrine et al.
    β2-adrenergic receptors control glucose metabolism by regulating cross-talk between pancreatic islet endocrine cells and vasculature during development.
    1. Developmental Biology

    The vascular niche controls Drosophila hematopoiesis via fibroblast growth factor signaling

    Manon Destalminil-Letourneau et al.
    Two niches contribute to the control of Drosophila blood cell homeostasis through their differential regulation of hematopoietic progenitors.

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