593 results found
  1. The Author's Story

    The Author's Story: A Series of Interviews

    Edited by Emma Pewsey
    eLife authors answer questions about their life and work.
  2. December 2016

    Episode 34: December 2016

    In this episode we hear about fossil footprints, taking medical research to the clinic, sleepy flies, team-working ants and diversity in science.
  3. Footprints of the past

    Episode 35: Footprints of the past

    In this special episode we hear the full story of the discovery of the fossil footprints in Laetoli, Tanzania, as featured in episode 34.
  4. The cone snail Conus geographicus eating a goby fish

    Episode 55: March 2019

    In this episode, we hear about fast-acting insulin in cone snails, the roots of addiction, new gene editing techniques and gender biases in joint first authors.
  5. August 2016

    Episode 31: August 2016

    In this episode we hear about human height, fish joints, colour vision, chimpanzees using tools and open science.
  6. Meet <i>Homo naledi</i>

    Episode 23: Meet Homo naledi

    In this special episode we hear about a new human species, Homo naledi, that has been unearthed from the Rising Star cave system in South Africa.
    1. Cell Biology
    2. Developmental Biology

    Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation

    Pieter R Norden et al.
    Genetic and molecular analyses show that FOXC1 and FOXC2 play a role in controlling lymphatic valve maintenance as key mediators of mechanotransduction to control cytoskeletal organization and RhoA/ROCK signaling.
    1. Microbiology and Infectious Disease

    Comprehensive annotations of human herpesvirus 6A and 6B genomes reveal novel and conserved genomic features

    Yaara Finkel et al.
    Unbiased mapping of viral open reading frames (ORFs) and transcripts in HHV-6 genomes uncovers novel ORFs and lncRNAs that are conserved across betaherpesviruses.
    1. Cell Biology
    2. Immunology and Inflammation

    Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion

    Danielle J Clark et al.
    A membrane-associated, supramolecular protein complex with dynamically changing components, the central supramolecular activation cluster, regulates the generation of the T cell effector cytokine IL-2 depending on its composition.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei

    Ali H Alghamdi et al.
    Study of TbAQP2 adaptations and substrate interactions shows how this aquaglyceroporin enables cellular entry of large antimicrobial agents in Trypanosoma brucei.

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