11 results found
    1. Neuroscience

    The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice

    Xiang-Chun Ju, Qiong-Qiong Hou ... Zhen-Ge Luo
    Introducing a hominoid-specific gene into mice induces cortical folding.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Tempo and mode of gene expression evolution in the brain across primates

    Katherine Rickelton, Trisha M Zintel ... Courtney C Babbitt
    Larger phylogenetic context is required to understand human and nonhuman primate brain evolution.
    1. Evolutionary Biology

    Evolutionary transcriptomics implicates new genes and pathways in human pregnancy and adverse pregnancy outcomes

    Katelyn Mika, Mirna Marinić ... Vincent J Lynch
    Comparative studies of gene expression in the uterus during pregnancy identifies new genes important for pregnancy and associated with complications such as preterm birth.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells

    Kei Fukuda, Yoshinori Makino ... Yoichi Shinkai
    Bioinformatics analyses reveal that the Krüppel-associated box domain zinc finger proteins are associated with DNA methylation of retroelements in human primordial germ cells which highlight potential molecular mechanisms for the regulation of retroelements in human male germ cells.
    1. Evolutionary Biology
    2. Neuroscience

    The evolution and biological correlates of hand preferences in anthropoid primates

    Kai R Caspar, Fabian Pallasdies ... Sabine Begall
    Primate hand preference strength but not direction (left vs. right) generally reflects phylogeny and ecology at species level, but human handedness deviates markedly from all other species.
    1. Genetics and Genomics

    Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryo

    Thomas A Carter, Manvendra Singh ... Cédric Feschotte
    A 'phyloregulatory' approach reveals how human endogenous retrovirus type-H, a family of human endogenous retroviruses, diversified its regulatory sequences through multiple mutational mechanisms to partition its transcriptional activity spatially and temporally within the human embryo.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Evidence linking APOBEC3B genesis and evolution of innate immune antagonism by gamma-herpesvirus ribonucleotide reductases

    Sofia N Moraes, Jordan T Becker ... Reuben S Harris
    The birth of the antiviral gene APOBEC3B in ancient primates is linked to the evolution of a potent counterdefense by herpesviruses, a host-pathogen interaction maintained to present day.
    1. Genetics and Genomics
    2. Evolutionary Biology

    The integrated WF-Haldane (WFH) model of genetic drift resolving the many paradoxes of molecular evolution

    Yongsen Ruan, Xiaopei Wang ... Chung-I Wu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Evolutionary Biology
    2. Neuroscience

    Quantitative uniqueness of human brain evolution revealed through phylogenetic comparative analysis

    Ian F Miller, Robert A Barton, Charles L Nunn
    The exceptionally large size of the human brain is the result of accelerating evolution towards larger brains in hominins, but is not the product of neocortical expansion.
    1. Evolutionary Biology

    Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas

    Jacob D. Bowman, Neide Silva ... Vincent J. Lynch
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete

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