1,484 results found
    1. Ecology
    2. Epidemiology and Global Health

    Physiology and ecology combine to determine host and vector importance for Ross River virus

    Morgan P Kain et al.
    The role host and vector species play in pathogen transmission cycles is best quantified by integrating species' physiological and ecological competence.
    1. Developmental Biology
    2. Neuroscience

    Sox1a mediates the ability of the parapineal to impart habenular left-right asymmetry

    Ingrid Lekk et al.
    The sox1a gene is required for a small group on neurons on the left side of the brain to influence the generation and left-sided character of their future synaptic partners.
    1. Microbiology and Infectious Disease

    Predictors of SIV recrudescence following antiretroviral treatment interruption

    Mykola Pinkevych et al.
    The frequency of SIV reactivation from latency after treatment interruption is not directly related to measures of SIV DNA, RNA, immune activation or immune response in peripheral blood.
    1. Cell Biology

    SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation

    David W Sanders et al.
    A high-throughput microscopy screen for drugs that modulate SARS-CoV-2 spike-mediated membrane fusion identifies an essential role for cholesterol in both virus entry and syncytia formation.
    1. Computational and Systems Biology
    2. Ecology

    Data-driven identification of potential Zika virus vectors

    Michelle V Evans et al.
    Data-driven methods predict over 35 mosquitoes are potential vectors of Zika virus, suggesting a larger geographic area and a greater human population is at risk of infection.
    1. Neuroscience

    Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming in C. elegans

    Haowen Liu et al.
    RIM binding UNC-13L C2A domain releases UNC-13L from an autoinhibitory homodimeric complex to become fusion-competent, and regulates probability of synaptic vesicle release in the post-priming process.
    1. Cell Biology
    2. Developmental Biology

    Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner

    Sun-Hee Hwang et al.
    Signaling specifically in cilia by a cAMP generating G-protein-coupled receptor directs tissue-specific morphogenesis.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Region-specific regulation of stem cell-driven regeneration in tapeworms

    Tania Rozario et al.
    Tapeworms grow and regenerate using stem cells distributed throughout their bodies, but their regeneration competence relies upon the unique micro-environment created by the head and neck.
    1. Cell Biology
    2. Developmental Biology

    Alstrom syndrome gene is a stem-cell-specific regulator of centriole duplication in the Drosophila testis

    Cuie Chen, Yukiko M Yamashita
    Alms1a is a centrosomal protein that exhibits asymmetric localization between mother and daughter centrosomes in asymmetrically dividing stem cells in Drosophila testis, controlling centriole duplication.
    1. Developmental Biology

    Antagonistic control of Caenorhabditis elegans germline stem cell proliferation and differentiation by PUF proteins FBF-1 and FBF-2

    Xiaobo Wang et al.
    Complementary effects of FBF-1 and FBF-2 on germline stem cell dynamics result from their distinct cooperation with mRNA deadenylase resulting in the opposite effects on the shared target mRNAs.

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