251 results found
    1. Microbiology and Infectious Disease

    Secretory leukocyte protease inhibitor influences periarticular joint inflammation in B. burgdorferi-infected mice

    Qian Yu, Xiaotian Tang ... Erol Fikrig
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Plant Biology

    The phytoplasma SAP54 effector acts as a molecular matchmaker for leafhopper vectors by targeting plant MADS-box factor SVP

    Zigmunds Orlovskis, Archana Singh ... Saskia A Hogenhout
    Phytoplasma effector SAP54 hijacks previously unknown MADS-box protein roles in plant-insect interactions by modulating plant biotic stress responses to male leafhoppers and facilitating female attraction and reproduction on male-exposed leaves.
    1. Microbiology and Infectious Disease

    Prophage regulation of Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta

    Ojas Natarajan, Susanne L Gibboney ... Larry J Dishaw
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    SICKO: Systematic Imaging of Caenorhabditis Killing Organisms

    Luis S Espejo, Samuel Freitas ... George L Sutphin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Plant Biology

    The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus

    Hanbin Bao, Yanan Wang ... Yangrong Cao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Evolutionary Biology

    Discarded sequencing reads uncover natural variation in pest resistance in Thlaspi arvense

    Dario Galanti, Jun Hee Jung ... Oliver Bossdorf
    Aphid and mildew read counts leftover from the sequencing of greenhouse plants correlated with the environment of origin of the plants, and allowed the mapping of pathogen resistance genes.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    The physiological landscape and specificity of antibody repertoires are consolidated by multiple immunizations

    Lucia Csepregi, Kenneth Hoehn ... Sai T Reddy
    Systems analysis of antibody repertoires reveals that strong humoral responses lead to extensive B-cell overlap across multiple lymphoid organs, indicating physiological axes of B-cell migration and a direct correlation with antigen specificity.
    1. Microbiology and Infectious Disease

    Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens

    Francesca Torelli, Diogo M da Fonseca ... Moritz Treeck
    Secreted effector proteins of Toxoplasma gondii parasites create a supportive immune environment in mice, allowing individually less fit mutants to thrive and evade detection by in vivo CRISPR screens.
    1. Microbiology and Infectious Disease

    Human immunodeficiency virus-1 induces host genomic R-loops and preferentially integrates its genome near the R-loop regions

    Kiwon Park, Dohoon Lee ... Kwangseog Ahn
    Investigation of the role of triple-stranded nucleic acid, R-loops, in HIV-1 genome integration.
    1. Medicine
    2. Neuroscience

    Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with severe alcohol use disorder

    Sophie Leclercq, Hany Ahmed ... Nathalie Delzenne
    Metabolomics analysis identified potential neuroactive metabolites, issued from food and microbial fermentation, that are linked to symptoms of depression, anxiety and alcohol craving.

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