643 results found
    1. Stem Cells and Regenerative Medicine
    2. Microbiology and Infectious Disease

    Stem cell progeny contribute to the schistosome host-parasite interface

    James J Collins III, George R Wendt ... Phillip A Newmark
    Stem cells are found to continually rejuvenate the epidermis of the human parasite Schistosoma mansoni.
    1. Microbiology and Infectious Disease

    The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion

    Christine R Collins, Fiona Hackett ... Michael J Blackman
    Genetic analysis identifies an enzyme of the malaria parasite that is required to seal its host red blood cell membrane upon invasion, a key requirement of this important intracellular pathogen.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Emergence and diversification of a host-parasite RNA ecosystem through Darwinian evolution

    Taro Furubayashi, Kensuke Ueda ... Norikazu Ichihashi
    In an in vitro RNA replication system, an RNA spontaneously diversifies and continuously evolves through coevolution with parasitic entities.
    1. Ecology
    2. Epidemiology and Global Health

    Ecological multiplex interactions determine the role of species for parasite spread amplification

    Massimo Stella, Sanja Selakovic ... Cecilia S Andreazzi
    Predators may amplify multiple-host parasite spreading in systems with multiple transmission routes.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

    Natalie A Counihan, Scott A Chisholm ... Tania F de Koning-Ward
    Plasmodium parasites secrete RhopH2 from the rhoptry organelle into their host red blood cell to facilitate the uptake of essential nutrients required for parasite replication and survival.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum

    Kathryn Milne, Alasdair Ivens ... Philip J Spence
    Parasite variants associated with severe malaria do not have an intrinsic growth or survival advantage in vivo, which indicates that a change in host environment is required for their selection.
    1. Genetics and Genomics
    2. Plant Biology

    Evidence for suppression of immunity as a driver for genomic introgressions and host range expansion in races of Albugo candida, a generalist parasite

    Mark McMullan, Anastasia Gardiner ... Jonathan DG Jones
    Hybridization and introgression blur species boundaries and broaden genetic diversity available for adaptation; and widespread introgression underpins the evolution of races of the generalist pathogen Albugo candida that specialise on different host plant species.
    1. Microbiology and Infectious Disease

    The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival

    Hui Dong, Jiong Yang ... Shaojun Long
    Combined cutting-edge technologies discovered a pair of carboxylate transporters that appears evolutionarily different among novel transporters and that is essential for parasite physiology.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    A new family of cell surface located purine transporters in Microsporidia and related fungal endoparasites

    Peter Major, Kacper M Sendra ... Robert P Hirt
    Transporters shared by fungal intracellular parasites provide new insights into the evolution of nucleotide and energy parasitism.
    1. Genetics and Genomics

    Codon optimization underpins generalist parasitism in fungi

    Thomas Badet, Remi Peyraud ... Sylvain Raffaele
    Codon optimization through biased synonymous substitutions is a characteristic feature of the genomes of generalist fungal parasites and is associated with the colonization of multiple hosts.

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