A novel statistical framework and approach using sibling phenotype pairs allows inference of genetic architecture in the tails of complex traits to be made without genetic data.
Felix Lankester, Tito J Kibona ... Sarah Cleaveland
Livestock abortion surveillance can capture valuable information on important livestock pathogens, including those that are zoonotic and with epidemic potential, revealing importance of timely collection of diagnostic samples for attribution.
The minimal twister sister (TS)-like self-cleaving ribozymes, revealed by deep mutational scanning, represent some of the very few human/primate ribozymes.
Nasa Sinnott-Armstrong, Stanley Fields ... Christine Queitsch
Multiplexed assays of variant effect are an increasingly important tool in genetic research and including more context specificity in their design would aid interpretation and discovery.
Bacillus velezensis has broad-spectrum antibacterial activity and can reduce the colonization of Salmonella Typhimurium in the intestinal tract of mice.
Chromatin immunoprecipitation sequencing and RNA sequencing have elucidated the complex transcript regulation pathways orchestrated by SntB, pivotal for Aspergillus flavus's development, mycotoxin production, and virulence.
