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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Stochastic processes constrain the within and between host evolution of influenza virus

    John T McCrone, Robert J Woods ... Adam S Lauring
    An analysis of influenza viruses from naturally infected people suggests a tight transmission bottleneck and little positive selection within hosts.
    1. Epidemiology and Global Health
    2. Medicine

    A stepped-wedge randomised trial on the impact of early ART initiation on HIV-patients’ economic outcomes in Eswatini

    Janina Isabel Steinert, Shaukat Khan ... Pascal Geldsetzer
    A stepped-wedge randomised controlled trial shows that early antiretroviral therapy (ART) initiation does not negatively affect the economic welfare of HIV patients in a low-income country.
    1. Epidemiology and Global Health

    Variation in natural exposure to anopheles mosquitoes and its effects on malaria transmission

    Wamdaogo M Guelbéogo, Bronner Pamplona Gonçalves ... Chris Drakeley
    Heterogeneity in exposure to malaria vectors, including sporozoite-infected mosquitoes, contributes to the variation in human infection risk and amplifies the local transmission potential.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Household clustering and seasonal genetic variation of Plasmodium falciparum at the community-level in The Gambia

    Marc-Antoine Guery, Sukai Ceesay ... Antoine Claessens
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Impact of the scale-up of piped water on urogenital schistosomiasis infection in rural South Africa

    Frank Tanser, Daniel K Azongo ... Christopher Appleton
    Scale-up of safe water supplies decreases a child's risk of urogenital schistosomiasis infection by eight-fold in a typical rural African population.
    1. Microbiology and Infectious Disease

    Cohabiting family members share microbiota with one another and with their dogs

    Se Jin Song, Christian Lauber ... Rob Knight
    Research on humans and dogs reveals that the communities of microorganisms found on the skin, on the tongue and in the intestine are affected differently by age and cohabitation.
    1. Epidemiology and Global Health

    Quantification of anti-parasite and anti-disease immunity to malaria as a function of age and exposure

    Isabel Rodriguez-Barraquer, Emmanuel Arinaitwe ... Bryan Greenhouse
    Analyses of detailed clinical and entomological data from cohort studies reveal how anti-parasite and anti-disease immunity against P. falciparum develop as a function of age and transmission intensity.
    1. Epidemiology and Global Health

    Parental vaccination to reduce measles immunity gaps in Italy

    Valentina Marziano, Piero Poletti ... Stefano Merler
    Offering measles vaccination to parents who bring their children to receive any dose of measles vaccine can accelerate measles elimination in Italy.
    1. Epidemiology and Global Health
    2. Medicine

    Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: A controlled before-and-after trial

    Jackie Knee, Trent Sumner ... Joe Brown
    Onsite sanitation maybe insufficient to interrupt transmission of enteric infections in high-burden urban settings, though risk of some infections may be reduced among children protected from birth.
    1. Epidemiology and Global Health

    Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study

    David W Eyre, Sheila F Lumley ... Timothy M Walker
    Risk factors for SARS-CoV-2 infection in healthcare workers included caring for Covid-19 patients, Black or Asian ethnicity, and Covid-19-positive household contacts, whereas a bundle of PPE-related measures protected ICU staff.